MED13 Antibody

Images

 
Independent Antibodies: Western Blot: MED13 Antibody [NB100-60642] - Whole cell lysate from HeLa and 293T cells. THRAP1/TRAP240 was also immunoprecipitated by rabbit anti-THRAP1/TRAP240 antibody NB100-60641.

Product Details

Summary
Reactivity Hu, PmSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.2 mg/ml

Order Details

MED13 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 750 and 800 of human thyroid hormone receptor associated protein 1 (thyroid hormone receptor-associated protein, 240 kDa) using the numbering given in entry NP_005112.2 (GeneID 996
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MED13
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunoprecipitation 2-5 ug/mg lysate
Publications
Read Publications using
NB100-60642 in the following applications:

  • WB
    1 publication

Reactivity Notes

Primate reactivity reported in scientific literature (PMID: 24147125).

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for MED13 Antibody

  • Activator-recruited cofactor 250 kDa component
  • KIAA0593HSPC221
  • mediator complex subunit 13ARC250
  • mediator of RNA polymerase II transcription, subunit 13 homolog
  • THRAP1mediator of RNA polymerase II transcription subunit 13
  • thyroid hormone receptor associated protein 1
  • Thyroid hormone receptor-associated protein 1
  • Thyroid hormone receptor-associated protein complex 240 kDa component
  • thyroid hormone receptor-associated protein complex component TRAP240
  • thyroid hormone receptor-associated protein, 240 kDa subunit
  • Trap240
  • TRAP240DRIP250
  • Vitamin D3 receptor-interacting protein complex component DRIP250

Background

This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. The product of this gene is proposed to form a sub-complex with MED12, cyclin C, and CDK8 that can negatively regulate transactivation by mediator.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for MED13 Antibody (NB100-60642)(2)

We have publications tested in 1 confirmed species: Primate.

We have publications tested in 1 application: WB.


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WB
(1)
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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

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Additional MED13 Products

Array NB100-60642

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Bioinformatics

Gene Symbol MED13
Entrez
Uniprot