Independent Antibodies: Western Blot: MED13 Antibody [NB100-60642] - Whole cell lysate from HeLa and 293T cells. THRAP1/TRAP240 was also immunoprecipitated by rabbit anti-THRAP1/TRAP240 antibody NB100-60641.
The immunogen recognized by this antibody maps to a region between residue 750 and 800 of human thyroid hormone receptor associated protein 1 (thyroid hormone receptor-associated protein, 240 kDa) using the numbering given in entry NP_005112.2 (GeneID 996
Immunogen affinity purified
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Vitamin D3 receptor-interacting protein complex component DRIP250
This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. The product of this gene is proposed to form a sub-complex with MED12, cyclin C, and CDK8 that can negatively regulate transactivation by mediator.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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