CX3CL1/Fractalkine Antibody [HRP]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications IHC-Fr, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
HRP

CX3CL1/Fractalkine Antibody [HRP] Summary

Immunogen
A genomic peptide made to an internal region of the human CX3CL protein (within residues 20-150). [Swiss-Prot P78423]
Localization
Cell membrane; Single-pass type I membrane protein. (Processed fractalkine: Secreted).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CX3CL1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
Application Notes
This CX3CL1 antibody is useful for IHC and ICC. Immunohistochemistry-Frozen was reported in scientific literature.
Readout System

Reactivity Notes

Human and mouse.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
No Preservative
Purity
Immunogen affinity purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CX3CL1/Fractalkine Antibody [HRP]

  • ABCD-3
  • C3Xkine
  • chemokine (C-X3-C motif) ligand 1
  • CX3C membrane-anchored chemokine
  • CX3CL1
  • CXC3
  • CXC3C
  • FKN
  • Fractalkine
  • Neurotactin
  • neurotactin)
  • NTNsmall inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine
  • NTTSmall-inducible cytokine D1
  • SCYD1C-X3-C motif chemokine 1
  • small inducible cytokine subfamily D (Cys-X3-Cys), member-1

Background

CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively, (1-4). The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1 (5). Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine (6). CX3CR1 mediates leukocyte migration and adhesion (5). CX3CR1 is expressed in a variety of human tissues and cell lines (2).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics Tool for CX3CL1/Fractalkine Antibody (NBP1-49539H)

Discover related pathways, diseases and genes to CX3CL1/Fractalkine Antibody (NBP1-49539H). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for CX3CL1/Fractalkine Antibody (NBP1-49539H)

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Bioinformatics

Gene Symbol CX3CL1
Entrez