CX3CL1/Fractalkine Antibody [FITC]


There are currently no images for CX3CL1/Fractalkine Antibody (NBP1-49539F).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Reactivity Hu, MuSpecies Glossary
Applications IHC
Please see the vial label for concentration. If unlisted please contact technical services.

CX3CL1/Fractalkine Antibody [FITC] Summary

A genomic peptide made to an internal region of the human CX3CL protein (within residues 20-150). [Swiss-Prot P78423]
Cell membrane; Single-pass type I membrane protein. (Processed fractalkine: Secreted).
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Store at 4C in the dark.
FITC (A=495, E=519)
0.05% Sodium Azide
Immunogen affinity purified


  • Immunohistochemistry 1:250
Application Notes
This CX3CL1 antibody is useful for IHC and ICC. Immunohistochemistry-Frozen was reported in scientific literature.

Reactivity Notes

Human and mouse.

Alternate Names for CX3CL1/Fractalkine Antibody [FITC]

  • ABCD-3
  • C3Xkine
  • chemokine (C-X3-C motif) ligand 1
  • CX3C membrane-anchored chemokine
  • CXC3
  • CXC3C
  • FKN
  • Fractalkine
  • Neurotactin
  • neurotactin)
  • NTNsmall inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine
  • NTTSmall-inducible cytokine D1
  • SCYD1C-X3-C motif chemokine 1
  • small inducible cytokine subfamily D (Cys-X3-Cys), member-1


As the only member of intercrine delta/ CX3C family, CX3CR1 (C-X3-C motif chemokine 1) is a type I transmembrane protein with CX3C chemokine domain present on an extended glycosylated stalk and it share this unique membrane anchorage with CXCR6 ligand, CXCL16. CX3CL1 is constitutively shed from the cell surface by ADAM10 (A Disintegrin and Metalloprotease 10) and CX3CL1 cleavage is enhanced upon activation of the closely related protease TNFalpha-converting enzyme, TACE (ADAM-17). CX3CL1 is expressed in a wide variety of cell types including neurons, intestinal, airway, skin epithelium cells, airway smooth muscle cells, and endothelium. It is induced by TNF and IL1 in pulmonary endothelial cells and umbilical vein endothelial cells. CX3CL1 signals through CX3CR1 (the only receptor of CX3CL1) which is expressed on monocytes, natural killer cells, T cells and smooth muscle cells. The major function of CX3CL1's soluble form is to act as chemotactic for T-cells and monocytes, but not for neutrophils, whereas, the membrane-bound form promotes adhesion of those leukocytes to endothelial cells where it may play a role in regulating leukocyte adhesion and migration processes at the endothelium. In addition to its role in chemotaxis and adhesion of leukocytes, CX3CL1 implicates in survival of multiple cell types during homeostasis and inflammation.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

Species: Hu, Mu, Rt
Applications: ELISA, Flow, ICC/IF, IHC, IHC-P
Species: Hu, Pm
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP
Species: Hu, Rt, Ca, Mk
Applications: WB, IHC, IHC-P, IP
Species: Hu, Mu
Applications: WB, Simple Western
Species: Hu
Applications: WB, ELISA(Cap), ELISA(Det), ICC, ICFlow, Neut, ELISA(Sta)
Species: Mu
Applications: WB, IHC

Publications for CX3CL1/Fractalkine Antibody (NBP1-49539F) (0)

There are no publications for CX3CL1/Fractalkine Antibody (NBP1-49539F).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for CX3CL1/Fractalkine Antibody (NBP1-49539F) (0)

There are no reviews for CX3CL1/Fractalkine Antibody (NBP1-49539F). By submitting a review earn points towards our Rewards Program.
  • 250 points for product review
  • 500 additional points for an image with your product review
  • Double points (500) if you are the first to review this product
  • Double points (1000) if you are the first to review this product with an image

FAQs for CX3CL1/Fractalkine Antibody (NBP1-49539F) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies


Isotype Controls

Additional CX3CL1/Fractalkine Antibody [FITC] Products

Related Products by Gene

Bioinformatics Tool for CX3CL1/Fractalkine Antibody (NBP1-49539F)

Discover related pathways, diseases and genes to CX3CL1/Fractalkine Antibody (NBP1-49539F). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for CX3CL1/Fractalkine Antibody (NBP1-49539F)

Discover more about diseases related to CX3CL1/Fractalkine Antibody (NBP1-49539F).

Pathways for CX3CL1/Fractalkine Antibody (NBP1-49539F)

View related products by pathway.

PTMs for CX3CL1/Fractalkine Antibody (NBP1-49539F)

Learn more about PTMs related to CX3CL1/Fractalkine Antibody (NBP1-49539F).

Research Areas for CX3CL1/Fractalkine Antibody (NBP1-49539F)

Find related products by research area.

Blogs on CX3CL1/Fractalkine

There are no specific blogs for CX3CL1/Fractalkine, but you can read our latest blog posts.

Contact Information

Product PDFs


Gene Symbol CX3CL1

Customer Resources

Novus Review - Submit your review and earn rewards points which can be used for merchandise & discounts.
Risk Free Testing - Test on a species/application not listed above to receive a full credit towards a future purchase.

Novus' Quality Guarantee - Novus guarantees that every product we sell will work in the application and species listed on our website and datasheets.

Submit your question on NBP1-49539F below.
During business hours, we will respond to your email within 24 hours. For any questions submitted on the weekend, a response will be received on Monday.
For immediate assistance during business hours M- F (excluding major holidays), please contact us.
Ask a Scientist - We have a lab full of white coats just waiting for your scientific questions and concerns.

Customers Who Bought This Also Bought

Mouse IL-4 Protein