CX3CL1/Fractalkine Antibody


Immunocytochemistry/ Immunofluorescence: CX3CL1/Fractalkine Antibody [NBP1-49539] - Analysis of CX3CL (green) in HeLa cells using NBP1-49539. Nuclei (blue) are counterstained using Hoechst 33258.
Immunohistochemistry: CX3CL1/Fractalkine Antibody [NBP1-49539] - Analysis of CX3CL in mouse brain.
Immunohistochemistry: CX3CL1/Fractalkine Antibody [NBP1-49539] - Analysis of CX3CL in mouse lung

Product Details

Reactivity Hu, MuSpecies Glossary
Applications ICC/IF, IHC, IHC-Fr, IHC-P
1.15 mg/ml

CX3CL1/Fractalkine Antibody Summary

A genomic peptide made to an internal region of the human CX3CL protein (within residues 20-150). [Swiss-Prot P78423]
Cell membrane; Single-pass type I membrane protein. (Processed fractalkine: Secreted).
Immunogen affinity purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.


  • Immunocytochemistry/Immunofluorescence 1:100
  • Immunohistochemistry 1:250
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin 1:250
Application Notes
This CX3CL1 antibody is useful for IHC and ICC. Immunohistochemistry-Frozen was reported in scientific literature.
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NBP1-49539 in the following applications:

Reactivity Notes

Human and mouse.

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS and 30% Glycerol
0.05% Sodium Azide
1.15 mg/ml
Immunogen affinity purified


Manufactured by Genomic Antibody Technology™. GAT FAQs

Alternate Names for CX3CL1/Fractalkine Antibody

  • ABCD-3
  • C3Xkine
  • chemokine (C-X3-C motif) ligand 1
  • CX3C membrane-anchored chemokine
  • CX3CL1
  • CXC3
  • CXC3C
  • FKN
  • Fractalkine
  • Neurotactin
  • neurotactin)
  • NTNsmall inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine
  • NTTSmall-inducible cytokine D1
  • SCYD1C-X3-C motif chemokine 1
  • small inducible cytokine subfamily D (Cys-X3-Cys), member-1


As the only member of intercrine delta/ CX3C family, CX3CR1 (C-X3-C motif chemokine 1) is a type I transmembrane protein with CX3C chemokine domain present on an extended glycosylated stalk and it share this unique membrane anchorage with CXCR6 ligand, CXCL16. CX3CL1 is constitutively shed from the cell surface by ADAM10 (A Disintegrin and Metalloprotease 10) and CX3CL1 cleavage is enhanced upon activation of the closely related protease TNFalpha-converting enzyme, TACE (ADAM-17). CX3CL1 is expressed in a wide variety of cell types including neurons, intestinal, airway, skin epithelium cells, airway smooth muscle cells, and endothelium. It is induced by TNF and IL1 in pulmonary endothelial cells and umbilical vein endothelial cells. CX3CL1 signals through CX3CR1 (the only receptor of CX3CL1) which is expressed on monocytes, natural killer cells, T cells and smooth muscle cells. The major function of CX3CL1's soluble form is to act as chemotactic for T-cells and monocytes, but not for neutrophils, whereas, the membrane-bound form promotes adhesion of those leukocytes to endothelial cells where it may play a role in regulating leukocyte adhesion and migration processes at the endothelium. In addition to its role in chemotaxis and adhesion of leukocytes, CX3CL1 implicates in survival of multiple cell types during homeostasis and inflammation.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CX3CL1/Fractalkine Antibody (NBP1-49539)(1)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 2 applications: ICC/IF, IHC-Fr.

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Product General Protocols

Video Protocols

ICC/IF Video Protocol

FAQs for CX3CL1/Fractalkine Antibody (NBP1-49539). (Showing 1 - 1 of 1 FAQ).

  1. I’ve purchased your CX3CL1 Antibody (NMP-49539). Could you please let me know what the concentration of this antibody is?
    • The current lot, A1, of our CX3CL1 antibody with catalogue number NBP1-49539 is 0.57mg/ml.

Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor 405 Labeled NBP1-49539AF405
Alexa Fluor 488 Labeled NBP1-49539AF488
Alexa Fluor 647 Labeled NBP1-49539AF647
Alexa Fluor 700 Labeled NBP1-49539AF700
Biotin Labeled NBP1-49539B
DyLight 405 Labeled NBP1-49539V
DyLight 488 Labeled NBP1-49539G
DyLight 550 Labeled NBP1-49539R
DyLight 650 Labeled NBP1-49539C
FITC Labeled NBP1-49539F
HRP Labeled NBP1-49539H

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Gene Symbol CX3CL1