Cullin 3 Antibody

Product Discontinued

Cullin 3 Antibody Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residue 225 and 275 of human cullin 3 using the numbering given in entry NP_003581.1 (GeneID 8452).
• Predicted Species: Mouse (100%), Rat (100%), Xenopus (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CUL3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:500-1:2000
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunoprecipitation 2-5 ug/mg lysate
• Application Notes: Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.
• Control:

  Cullin 3 Overexpression Lysate

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Tris-Citrate/Phosphate (pH 7.0 - 8.0)
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Cullin 3 Antibody

• CUL3
• CUL-3
• cullin 3
• cullin-3
• KIAA0617
• NEDAUS
• PHA2E

Background

Cullin 3 is a member of the family of human Cullin genes (CUL-1, -2, -3, -4a, -4b and -5) homologous to the S. cerevisiae cdc53 gene. Cullin 3 forms a tight complex with cyclin E and targets it for ubiquitination, which leads to its degradation by proteosomes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Cullin 3 Antibody (NB100-58787)(1)

Publication using NB100-58787

• White EA, Sowa ME, Tan MJ et al. Systematic identification of interactions between host cell proteins and E7 oncoproteins from diverse human papillomaviruses. Proc Natl Acad Sci U S A 2012-01-01 [PMID: 22232672]

Bioinformatics

• Gene Symbol: CUL3
• Entrez:
  • 8452(Human)
• Uniprot:
  • Q13618(Human)