CTNNBL1 Antibody - BSA Free

Western Blot: CTNNBL1 Antibody [NBP1-76543] - Analysis in human brain tissue lysate with antibody at 0.5 ug/mL.

Immunocytochemistry/ Immunofluorescence: CTNNBL1 Antibody - BSA Free [NBP1-76543] - Immunofluorescence of CTNNBL1 in mouse brain tissue with CTNNBL1 antibody at 20 ug/mL.

Immunohistochemistry: CTNNBL1 Antibody - BSA Free [NBP1-76543] - Immunohistochemistry of CTNNBL1 in mouse brain tissue with CTNNBL1 antibody at 5 ug/mL.

• Reactivity: Hu, Mu, Rt, Bv
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

CTNNBL1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit CTNNBL1 Antibody - BSA Free (NBP1-76543) is a polyclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human CTTNBL1. The immunogen is located within the last 50 amino acids of CTTNBL1. Amino Acid Squence: YAENIGDGRSPEFRENEQKR
• Specificity: CTNNBL1 antibody is predicted to not cross-react with other catenin family members. At least four isoforms of CTNNBL1 are known to exist; this antibody will detect all but isoform b.
• Predicted Species: Bovine (95%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CTNNBL1
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 20 ug/ml
  • Immunohistochemistry 5 ug/ml
  • Immunohistochemistry-Paraffin 5 ug/ml
  • Western Blot 1-2 ug/ml
• Theoretical MW: 63 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
• Control Peptide:

  CTNNBL1 Peptide (NBP1-76543PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for CTNNBL1 Antibody - BSA Free

• beta-catenin-like protein 1
• C20orf33
• catenin, beta like 1
• dJ633O20.1
• FLJ21108
• NAPchromosome 20 open reading frame 33
• nuclear associated protein
• Nuclear-associated protein
• NYD-SP19
• P14
• P14L
• PP8304
• Testis development protein NYD-SP19

Background

The Beta-catenin-like protein 1 (CTNNBL1) contains an acidic domain, a putative bipartite nuclear localization signal, a nuclear export signal, a leucine-isoleucine zipper, and phosphorylation motifs, as well as Armadillo/beta-catenin-like repeats. Transient expression of CTNNBL1 resulted in translocation to the nucleus and apoptosis, suggesting it may be involved in the apoptotic pathway. CTNNBL1 interacts with the Prp19 complex of the spliceosome and the Ig class switching enzyme activation-induced deaminase (AID) and had been suggested to play a role in antibody-diversification and class switching, but recent studies have shown CTNNBL1 to be dispensable for Ig class switch recombination. Other studies have identified CTTNBL1 as a novel gene for obesity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CTNNBL1
• Uniprot:
  • NP_110517(Human)