CRTAC1 Antibody (755315) [Alexa Fluor® 750]

• Reactivity: Hu
• Applications: ICC/IF
• Clone: 755315
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 750

CRTAC1 Antibody (755315) [Alexa Fluor® 750] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human CRTAC1
  Ser28-Cys661
  Accession # Q9NQ79
• Specificity: Detects human CRTAC1 in direct ELISAs.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CRTAC1 Antibody (755315) [Alexa Fluor® 750]

• ASPIC
• ASPIC1
• ASPIC1CEP-68acidic secreted protein in cartilage
• cartilage acidic protein 1
• CEP68
• chondrocyte expressed protein 68 kDa CEP-68,68 kDa chondrocyte-expressed protein
• CRTAC1
• FLJ10320

Background

CRTAC1 (cartilage acidic protein 1; also CEP-68) is a 95‑105 kDa member of a novel family of EGF domain-containing proteins. It is secreted by articular chondrocytes and may play a role in either cartilage matrix organization or cell-matrix adhesion. Mature human CRTAC1 is 634 amino acids (aa) in length. It contains four FG-GAP (PheGly-GlyAlaPro) domains (aa 46‑437) and one EGF-like motif (aa 559‑605). Multiple splice forms exist. There are two alternate start sites at Met9 and Met211 that may be accompanied by a 39 aa substitution for the C-terminal 55 aa, or an 84 aa substitution for aa 545‑661. Over aa 28‑661, human CRTAC1 shares 91% aa identity with mouse CRTAC1. This form in mouse, however, is more equivalent to the human isoform that shows a C-terminal 39 aa substitution. In this case, there is 95% aa identity between mouse and human.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.