CPSF73 Antibody

Western Blot: CPSF73 Antibody [NBP2-15992] - Sample (30 ug of whole cell lysate) A: A431 7. 5% SDS PAGE gel, diluted at 1:2000.

• Reactivity: Hu, Mu, Rt, Bv, Pm, Xp, Ze
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

CPSF73 Antibody Summary

• Immunogen: Recombinant protein encompassing a sequence within the center region of human CPSF73. The exact sequence is proprietary.
• Localization: Nucleus
• Predicted Species: Mouse (99%), Rat (98%), Xenopus (98%), Primate (99%), Zebrafish (96%), Bovine (99%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CPSF3
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:3000
• Theoretical MW: 77 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Chimpanzee (99%), Xenopus laevis (98%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7), 20% Glycerol, 1% BSA
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for CPSF73 Antibody

• cleavage and polyadenylation specific factor 3, 73kD subunit
• cleavage and polyadenylation specific factor 3, 73kDa
• cleavage and polyadenylation specificity factor 3
• Cleavage and polyadenylation specificity factor 73 kDa subunit
• cleavage and polyadenylation specificity factor subunit 3
• CPSF 73 kDa subunit
• CPSF3
• CPSF73
• CPSF-73
• CPSF73CPSF
• EC 3.1.27
• EC 3.1.27.-
• mRNA 3'-end-processing endonuclease CPSF-73
• YSH1

Background

Most eukaryotic mRNA precursors (pre-mRNAs) undergo extensive maturational processing, including cleavage and polyadenylation at the 3-prime end. CPSF3 encodes the 73-kD subunit of the cleavage and polyadenylation specificity factor (CPSF) and is the pre-mRNA 3-prime-end-processing endonuclease (Mandel et al., 2006 [PubMed 17128255]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: CPSF3
• Uniprot:
  • Q9UKF6(Human)