CPOX Antibody (36B10) [DyLight 350]

• Reactivity: Hu
• Applications: WB, ELISA, ICC/IF
• Clone: 36B10
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 350

CPOX Antibody (36B10) [DyLight 350] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: Recombinant human CPOX (111-454aa) purified from E. coli
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: CPOX
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NBP2-59438. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Reactivity Notes

0

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for CPOX Antibody (36B10) [DyLight 350]

• Coprogen oxidase
• coproporphyrinogen oxidase
• coproporphyrinogenase
• coproporphyrinogen-III oxidase, mitochondrial
• COX
• CPO
• CPXcoproporphyrinogen oxidase (coproporphyria, harderoporphyria)
• EC 1.3.3.3
• HCP

Background

The protein encoded by the CPOX gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is solubleand found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation ofcoproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditarycoproporphyria (HCP).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CPOX