CPEB1 Antibody - BSA Free

Western Blot: CPEB1 Antibody [NBP1-76365] - Rat brain tissue lysate with CPEB1 antibody at (A) 1 and (B) 2 ug/ml.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

CPEB1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit CPEB1 Antibody - BSA Free (NBP1-76365) is a polyclonal antibody validated for use in WB and ELISA. Anti-CPEB1 Antibody: Cited in 2 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human CPEB1. The immunogen is located within amino acids 50 - 100 of CPEB1. Amino Acid Squence: LPDFQDSEETVTSR
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CPEB1
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot 1-2 ug/ml
• Control Peptide:

  CPEB1 Peptide (NBP1-76365PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for CPEB1 Antibody - BSA Free

• CPEBCEBP
• CPE-binding protein 1
• CPE-BP1
• cytoplasmic polyadenylation element binding protein 1
• cytoplasmic polyadenylation element-binding protein 1
• FLJ13203
• h-CEBP
• hCPEB-1
• MGC34136
• MGC60106

Background

CPEB1 is an RNA binding protein that contains an RNA-recognition motif and a zinc finger-containing region found in a wide range of vertebrates and invertebrates. CPEB1 forms the nucleus of a complex of factors that regulate poly(A) elongation and promotes polyadenylation-induced translation. CPEB1 mediates many diverse biological processes such as germ cell development, cell division and senescence, and synaptic plasticity. Recently, it was discovered that CPEB1 is involved in beta-catenin mRNA translation and cell migration in astrocytes as well as regulating hypoxia-inducible factor (HIF)-1 expression, demonstrating the wide range of processes in which CPEB1 plays a role. At least four isoforms of CPEB1 are known to exist.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CPEB1 Antibody (NBP1-76365)(2)

Publications using NBP1-76365

• Jones KJ, Korb E, Kundel MA et al. CPEB1 regulates beta-catenin mRNA translation and cell migration in astrocytes. Glia; 56:1401-13. 2008-01-01 [PMID: 18618654]
• Richter JD. CPEB: a life in translation. Trends in Biochem. Sci. 32:179-85. 2007-01-01 [PMID: 17481902]

Bioinformatics

• Gene Symbol: CPEB1
• Entrez:
  • 64506(Human)
  • 12877(Mouse)
  • 293056(Rat)
• Uniprot:
  • Q9BZB8(Human)