Immunohistochemistry: Corticotropin Releasing Factor Antibody [NB110-81721] - Immunohistochemical detection of Corticotropin Releasing Factor in Rat Hypothalamic Brain Tissue using a 1ug/ml dilution of Affinity Purified ...read more
This antibody recognises CRF in Human, Rat and Mouse. There is no Cross-reactivity with Guinea Pig.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -80C long term. Avoid freeze-thaw cycles.
Immunogen affinity purified
Reconstitute with 0.02 ml sterilized water.
Alternate Names for Corticotropin Releasing Factor Antibody - Azide and BSA Free
corticotropin releasing hormone
Corticotropin-releasing hormone (CRH) is a 41-amino acid peptide derived from a 191-amino acid preprohormone. CRH issecreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in CRH hasbeen observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin dificiency hasmultiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to productionin the hypothalamus, CRH is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed inthe placenta. In the placenta CRH is a marker that determines the length of gestation and the timing of parturitionand delivery. A rapid increase in circulating levels of CRH occurs at the onset of parturition, suggesting that, inaddition to its metabolic functions, CRH may act as a trigger for parturition. (provided by RefSeq)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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