Cortactin Antibody (SC61-08) Summary
Additional Information |
Recombinant Monoclonal Antibody. |
Immunogen |
Synthetic peptide within Human Cortactin aa 34-67 / 550. (SwissProt: Q14247 Human; SwissProt: Q60598 Mouse; Unigene:107869 Rat) |
Localization |
Cytoplasm, Cell projection, Membrane. |
Isotype |
IgG |
Clonality |
Monoclonal |
Host |
Rabbit |
Gene |
CTTN |
Purity |
Protein A purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Flow Cytometry 1:50-1:100
- Immunocytochemistry/Immunofluorescence 1:100-1:500
- Immunohistochemistry
- Immunohistochemistry-Paraffin 1:50-1:200
- Immunoprecipitation
- Western Blot 1:500-1:5000
|
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer |
TBS (pH7.4), 0.05% BSA, 40% Glycerol |
Preservative |
0.05% Sodium Azide |
Concentration |
1 mg/ml |
Purity |
Protein A purified |
Alternate Names for Cortactin Antibody (SC61-08)
Background
Immunocytochemistry reveals that in epithelial cells, the human cortactin protein is localized mainly in the cytoplasm and, to a very low extent, in protruding leading lamellae of the cell. However, in carcinoma cells that constitutively overexpress cortactin accumulates in the podosome-like adherens junctions associated with the cell-substratum contact sites. Overexpression and concomitant accumulation of the Cortactin protein in the cell-substratum contact sites might, therefore, contribute to the invasive potential of these tumor cells (1). In cells derived from breast carcinomas and squamous carcinomas of the head and neck, DNA amplification of a particular tyrosine kinase substrate region results in overexpression of cortactin. Overexpression is accompanied by a partial redistribution of cortactin from the cytoplasm into cell-matrix contact sites (2).
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
Customers Who Viewed This Item Also Viewed...
Species: Hu
Applications: IHC, Simple Western, WB
Species: Hu
Applications: ELISA, IHC, IHC-P, S-ELISA, WB
Species: Hu, Pm, Mu, Rt
Applications: Flow, ICC/IF, IHC, IHC-P, WB
Species: Mu
Applications: IHC, WB
Species: Hu, Mu
Applications: ICC/IF, IHC, IHC-P, WB
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, WB
Species: Hu, Mu, Rt
Applications: IHC, KO, WB
Species: Hu
Applications: CyTOF-ready, ELISA(Cap), ELISA(Det), ELISA(Sta), Flow, ICC, IHC, IP, Simple Western, WB
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, KD, Simple Western, WB
Species: Hu
Applications: BA
Species: Hu, Mu, Rt
Applications: CyTOF-ready, IHC, ICFlow, Simple Western, WB
Species: Hu
Applications: Flow, ICC/IF, IHC, IHC-P, PEP-ELISA, WB
Species: Hu
Applications: BA
Species: Ca, Ch, Hu, Mu, Pm, Rb, Rt, RM, Xp, Ze
Applications: ICC/IF, WB
Species: Hu
Applications: BA
Species: Hu
Applications: ELISA, IHC, IHC-P, KD, PLA, S-ELISA, WB
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-Fr, IHC-P, WB
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, IP, MiAr, WB
Species: Hu, Pm, Mu, Rt
Applications: ELISA, Flow, ICC/IF, IHC, IHC-P, WB
Species: Ca, Hu, Pm, Mu, Rt
Applications: IHC, IHC-P, IP, WB
Publications for Cortactin Antibody (NBP2-67632) (0)
There are no publications for Cortactin Antibody (NBP2-67632).
By submitting your publication information earn gift cards and discounts for future purchases.
Reviews for Cortactin Antibody (NBP2-67632) (0)
There are no reviews for Cortactin Antibody (NBP2-67632).
By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
- Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
- Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
Product General Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
Video Protocols
FAQs for Cortactin Antibody (NBP2-67632) (0)
Secondary Antibodies
| |
Isotype Controls
|
Additional Cortactin Products
Bioinformatics Tool for Cortactin Antibody (NBP2-67632)
Discover related pathways, diseases and genes to Cortactin Antibody (NBP2-67632). Need help?
Read the
Bioinformatics Tool Guide for instructions on using this tool.
Diseases for Cortactin Antibody (NBP2-67632)
Discover more about diseases related to Cortactin Antibody (NBP2-67632).
| | Pathways for Cortactin Antibody (NBP2-67632)
View related products by pathway.
|
PTMs for Cortactin Antibody (NBP2-67632)
Learn more about PTMs related to Cortactin Antibody (NBP2-67632).
| | Research Areas for Cortactin Antibody (NBP2-67632)
Find related products by research area.
|
Blogs on Cortactin