COPG2 Antibody - BSA Free

Western Blot: COPG2 Antibody - BSA Free [NBP3-47555] - Mouse heart tissue were subjected to SDS PAGE followed by western blot with (COPG2 antibody) at dilution of 1:1000

Immunohistochemistry: COPG2 Antibody - BSA Free [NBP3-47555] - Immunohistochemistry of paraffin-embedded human heart using (COPG2 antibody) at dilution of 1:50

• Reactivity: Hu, Mu
• Applications: WB, ELISA, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

COPG2 Antibody - BSA Free Summary

• Immunogen: coatomer protein complex, subunit gamma 2. (Uniprot# Q9UBF2)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: COPG2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry 1:20-1:200
  • Western Blot 1:500-1:2000
• Theoretical MW: 98 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, 50% Glycerol, pH (7.3)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for COPG2 Antibody - BSA Free

• 2-COP
• coat protein, nonclathrin, gamma-2-cop
• coatomer protein complex, subunit gamma 2
• coatomer subunit gamma-2
• DKFZp761N09121
• FLJ11781
• Gamma-2-coat protein
• gamma-2-COP

Background

Coatomer proteins are involved in regulating transport between the endoplasmic reticulum (ER) and the Golgi complex and in intra-Golgi transport. There exist two Coatomer-Protein mechanisms (COPI and COPII) and although they have mechanistic parallels, they are molecularly distinct. The COPI coat is comprised of seven subunits (alpha-, beta-, beta'-, gamma-, delta-, epsilon-, and zeta-COP) in a complex called coatomer. Assembly of the coatomer (COPI) onto non-clathrin coated vesicles is regulated by ADP-ribosylation factor (ARF). Vesicle formation, budding, fusion, and disassembly is dependent on GDP-GTP exchange, COPI, and ARF. COPI has been shown to facilitate retrograde intracellular transport from the ER to the Golgi complex. By contrast, COPII facilitates anterograde transport between these subcellular organelles. COPII has been shown to be independently and selectively recruited to the ER relative to COPI subunits.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: COPG2