Complement Factor H-related 1/CFHR1/CFHL1 Antibody (4D7) - Azide and BSA Free

Sandwich ELISA: Complement Factor H-related 1/CFHR1/CFHL1 Antibody (4D7) [H00003078-M01] - Detection limit for recombinant GST tagged CFHR1 is approximately 1ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: ELISA, ICC/IF, IHC
• Clone: 4D7
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

Complement Factor H-related 1/CFHR1/CFHL1 Antibody (4D7) - Azide and BSA Free Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: CFHR1 (AAH16755.1, 19 a.a. ~ 330 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. EATFCDFPKINHGILYDEEKYKPFSQVPTGEVFYYSCEYNFVSPSKSFWTRITCTEEGWSPTPKCLRLCFFPFVENGHSESSGQTHLEGDTVQIICNTGYRLQNNENNISCVERGWSTPPKCRSTDTSCVNPPTVQNAHILSRQMSKYPSGERVRYECRSPYEMFGDEEVMCLNGNWTEPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITCRNGQWSEPPKCLHPCVISREIMENYNIALRWTAKQKLYLRTGESAEFVCKRGYRLSSRSHTLRTTCWDGKLEYPTCAKR
• Specificity: CFHL1 - complement factor H-related 1 (4D7)
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: CFHR1
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Sandwich ELISA
• Application Notes: It has been used for ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Complement Factor H-related 1/CFHR1/CFHL1 Antibody (4D7) - Azide and BSA Free

• BTA
• CFHL1FHR-1
• CFHLCFHR1P
• CFHR1
• complement factor H-related 1 pseudogene
• Complement Factor Hrelated 1
• Complement Factor H-related 1
• complement factor H-related protein 1
• FHR1
• FHR1CFHL1P
• H factor (complement)-like 1
• H factor (complement)-like 2
• H factor-like protein 1
• H36-1
• H36-2
• H-factor-like 1
• HFL1H36
• HFL2
• MGC104329

Background

The CFHL1 gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonasaeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed thatTuf acts as a virulence fac

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Complement Factor H-related 1/CFHR1/CFHL1 Antibody (H00003078-M01)(3)

Publications using H00003078-M01

• Felix P, Elena J, Ilse J et al. A Family Affair: Addressing the Challenges of Factor H and the Related Proteins. Front Immunol. 2021-03-30 [PMID: 33868311]
• NR Medjeral-T, H Moffitt, HJ Lomax-Brow, N Constantin, T Cairns, HT Cook, MC Pickering Glomerular Complement Factor H-Related Protein 5 (FHR5) Is Highly Prevalent in C3 Glomerulopathy and Associated With Renal Impairment Kidney Int Rep, 2019-06-19;4(10):1387-1400. 2019-06-19 [PMID: 31701048]
• Medjeral-Thomas NR, Troldborg A, Constantinou N et al. Progressive IgA Nephropathy Is Associated With Low Circulating Mannan-Binding Lectin-Associated Serine Protease-3 (MASP-3) and Increased Glomerular Factor H-Related Protein-5 (FHR5) Deposition. Kidney Int Rep 2017-11-29 [PMID: 29725647]

Bioinformatics

• Gene Symbol: CFHR1
• Entrez:
  • 3078(Human)
• Uniprot:
  • AAH16755(Human)