Complement Component C5aR1 Antibody

Immunohistochemistry-Paraffin: Complement Component C5a R1 Antibody [NLS3867] - Analysis of anti-C5AR1 / CD88 antibody with human bone marrow 4 ug/ml.

Immunohistochemistry-Paraffin: Complement Component C5a R1 Antibody [NLS3867] - Analysis of anti-C5AR1 / CD88 antibody with untransfected HEK293 kidney cells.

Immunohistochemistry-Paraffin: Complement Component C5a R1 Antibody [NLS3867] - Analysis of anti-C5AR1 / CD88 antibody with HEK293 human embryonic kidney cells.

Product Discontinued

Complement Component C5aR1 Antibody Summary

• Immunogen: Synthetic 18 amino acid peptide from N-terminal extracellular domain of human Complement Component C5aR1.
• Specificity: Human C5AR1 / CD88. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Chimpanzee (100%), Primate (94%), Monkey (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: C5AR1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry 1:10 - 1:500
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 4 - 36 ug/ml
• Control:

  Complement Component C5aR1 Overexpression Lysate

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (94%), Gibbon (89%), Orangutan (83%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Complement Component C5aR1 Antibody

• C5a anaphylatoxin chemotactic receptor
• C5A
• C5aR
• C5a-R
• C5AR1
• C5ARC5a anaphylatoxin receptor
• C5R1C5a ligand
• CD88 antigen
• CD88
• complement component 5 receptor 1 (C5a ligand)
• complement component 5 receptor 1
• complement component 5a receptor 1
• Complement Component C5a R1
• Complement Component C5aR1

Background

C5a Anaphylatoxin Receptor mediates the effects of one of the most potent chemotactic agents known, in a wide variety of inflammatory cell types. C5a receptor 1 has been implicated in asthma. C5a receptor 1 expression has been reported in myeloid blood cells, brain, liver, lung, spleen, heart, kidney, and intestinal tract. ESTs have been isolated from B-cell/lung/testis, nerve, and placenta libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: C5AR1
• Entrez:
  • 728(Human)