Complement Component C1qA Antibody (7H8)

Immunocytochemistry/Immunofluorescence: Complement Component C1qA Antibody (7H8) [NB200-539] - staining C1q (green) in human SHSY5Y cells by ICC/IF (Immunocytochemistry/immunofluorescence).

• Reactivity: Mu
• Applications: ELISA, ICC/IF, IHC
• Clone: 7H8
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Unconjugated
• Concentration: 0.1 mg/ml

Complement Component C1qA Antibody (7H8) Summary

• Description: Novus Biologicals Rat Complement Component C1qA Antibody (7H8) (NB200-539) is a monoclonal antibody validated for use in IHC and ICC/IF. Anti-Complement Component C1qA Antibody: Cited in 7 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Unfortunately, this information is considered to be commercially sensitive
• Localization: Cytoplasmic and Secreted
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Rat
• Gene: C1QA
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunoassay
  • Immunocytochemistry/ Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10
• Application Notes: IHC-Fr: 4% PFA fixed and sucrose infiltrated frozen tissue. 18h 4C, 0.133 ug/ml 7H8. IA: Antibody 7H8 can be used as capture and detection antibody. To detect bound C11, 1/100 diluted 7H8 was used. Dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.

Packaging, Storage & Formulations

• Storage: Store at 4C.
• Buffer: 0.2 um filtered solution in PBS and 0.1% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.1 mg/ml
• Purity: Protein G purified

Alternate Names for Complement Component C1qA Antibody (7H8)

• C1QA complement component 1, q subcomponent, A chain
• C1QA
• Complement Component C1qA

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Complement Component C1qA Antibody (NB200-539)(7)

Publications using NB200-539

• Ibrahim T, Wu P, Wang LJ et al. Sex-dependent differences in the genomic profile of lingual sensory neurons in na�ve and tongue-tumor bearing mice Scientific Reports 2023-08-12 [PMID: 37573456]
• Ibrahim T, Wu P, Wang LJ et al. Sex-dependent Differences in the Genomic Profile of Lingual Sensory Neurons in Naïve and Tongue-Tumor Bearing Mice bioRxiv : the preprint server for biology 2023-05-14 [PMID: 36711730] (IHC-Fr, Mouse)
• Ankeny, D et al. B cells produce pathogenic antibodies and impair recovery after spinal cord injury in mice. J Clin Invest , 119: 2990. 2009-01-01 [PMID: 19770513]
• Abbitt, K et al. Antibody ligation of murine Ly-6G induces neutropenia, blood flow cessation, and death via complement-dependent and independent mechanisms. J Leukoc Biol , 85: 55. 2009-01-01 [PMID: 18927400]
• Kang, Y et al. A Dominant Complement Fixation Pathway for Pneumococcal Polysaccharides Initiated by SIGN-R1 Interacting with C1q. Cell , 125: 47. 2006-01-01 [PMID: 16615889]
• Suresh_m et al. Role of the property of C-Reactive Protein to activate the classical pathway of complement in protecting mice from pneumococcal infection. J Immunol , 176: 4369. 2006-01-01 [PMID: 16547275]
• Zachrau, B et al. Antigen localization within the splenic marginal zone restores humoral immune response and IgG class switch in complement C4-deficient mice. Int Immunol , 16: 1685. 2004-01-01 [PMID: 15477230]

Bioinformatics

• Gene Symbol: C1QA
• Entrez:
  • 12259(Mouse)