COLQ Antibody

Western Blot: COLQ Antibody [NBP2-14915] - Sample (30 ug of whole cell lysate) A: HepG2 10% SDS PAGE; antibody diluted at 1:1000.

Immunohistochemistry-Paraffin: COLQ Antibody [NBP2-14915] - Paraffin-embedded Colon ca, using antibody at 1:500 dilution.

• Reactivity: Hu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

COLQ Antibody Summary

• Immunogen: Recombinant protein encompassing a sequence within the center region of human COLQ. The exact sequence is proprietary.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: COLQ
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
• Theoretical MW: 48 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Mouse (87%), Rat (83%), Bovine (87%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Immunogen affinity purified

Alternate Names for COLQ Antibody

• acetylcholinesterase collagenic tail peptide
• AChE Q subunit
• collagenic tail of endplate acetylcholinesterase
• collagen-like tail subunit (single strand of homotrimer) of asymmetricacetylcholinesterase
• EADAcetylcholinesterase-associated collagen
• FLJ55041
• single strand of homotrimeric collagen-like tail subunit of asymmetricacetylcholinesterase

Background

This gene encodes the subunit of a collagen-like molecule associated with acetylcholinesterase in skeletal muscle. Each molecule is composed of three identical subunits. Each subunit contains a proline-rich attachment domain (PRAD) that binds an acetylcholinesterase tetramer to anchor the catalytic subunit of the enzyme to the basal lamina. Mutations in this gene are associated with endplate acetylcholinesterase deficiency. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: COLQ
• Uniprot:
  • Q9Y215(Human)