Collagen IV alpha 1 Antibody (COL-94)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
COL-94
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

Collagen IV alpha 1 Antibody (COL-94) Summary

Immunogen
Human collagen type IV
Localization
Basement membrane
Specificity
This antibody recognizes collagen type IV epitope located on the alpha1 and/or alpha 2 chains of human collagen type IV. This shows no cross reactivity with collagen types I, II, III, V, VI and VII and does not react with human vitronectin, fibronectin or chondroitin sulfate A, B and C.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
COL4A1
Purity
Unpurified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Ascites
Preservative
Sodium Azide
Purity
Unpurified

Alternate Names for Collagen IV alpha 1 Antibody (COL-94)

  • alpha-1 chain
  • arresten
  • COL4A1 NC1 domain
  • COL4A1
  • collagen alpha-1(IV) chain
  • Collagen IV alpha 1
  • collagen IV, alpha-1 polypeptide
  • collagen, type IV, alpha 1
  • Collagen-4
  • EC 3.4.23
  • EC 6.3.1.2

Background

Collagen IV is a major constituent of the basement membranes along with laminins, proteoglycans and enactins. It is a multimeric protein composed of 3 alpha subunits. These subunits are encoded by 6 different genes, alpha 1 through alpha 6, each of which can form a triple helix structure with 2 other subunits to form type IV collagen. It can form insoluble fibers with high tensile strength. Collagen IV is useful in detecting the loss of parts of basement membranes in carcinomas.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol COL4A1
Entrez