Canine Collagen II ELISA Kit

Product Discontinued

Canine Collagen II ELISA Kit Summary

• Description: For protocol and additional information on this kit, please see PDF products section on Novus website.
• Standard Curve Range: 100 to 1000 pM
• Sensitivity: 15 pM
• Inter-Assay: CV% < 20%
• Intra-Assay: CV% < 15%
• Spike Recovery: 104.3%
• Sample Volume: 50 uL
• Kit Type: ELISA Kit
• Gene: COL2A1

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: COLL2-1NO2 ELISA Kit measures a degradation fragment containing a 9 amino acid sequence (HRGYPGLDG) which is nitrated on the tyrosine residue [HRGY(NO2)PGLDG] of type II collagen molecule.

Reactivity Notes

Equine, Guinea Pig, Human, Mouse

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Canine Collagen II ELISA Kit

• Alpha-1 type II collagen
• ANFH
• AOM
• cartilage collagen
• Chondrocalcin
• COL11A3
• COL2A1
• Collagen 2
• collagen alpha-1(II) chain
• Collagen II
• collagen II, alpha-1 polypeptide
• collagen type 2
• collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphysealdysplasia, congenital)
• collagen, type II, alpha 1
• Collagen-2
• MGC131516
• SEDC

Background

The extensive family of COL gene products (collagens) is composed of several chain types, including fibril-forming interstitial collagens (types I, II, III and V) and basement membrane collagens (type IV), each type containing multiple isoforms. Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Several collagens also play a role in cell adhesion, important for maintaining normal tissue architecture and function. In cartilage, Collagen Type II constitutes the bulk of the fibril. Sensitization with Collagen Type II induces an erosive polyarthritis in rats, mice and higher primates which can resemble rheumatoid arthritis and relapsing polychrondritis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

FAQs for Collagen II ELISA Kit (KA2098). (Showing 1 - 1 of 1 FAQ).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: COL2A1