COL1A2 Antibody

Product Discontinued

COL1A2 Antibody Summary

• Immunogen: Synthetic peptide, corresponding to amino acids 461-510 of Human COL1A2.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: COL1A2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:50-1:200
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50-1:200
  • Western Blot 1:500-1:1000
• Theoretical MW: 125 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2)
• Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for COL1A2 Antibody

• alpha 2(I)-collagen
• Alpha-2 type I collagen
• collagen alpha-2(I) chain
• collagen I, alpha-2 polypeptide
• collagen of skin, tendon and bone, alpha-2 chain
• collagen, type I, alpha 2
• OI4
• osteogenesis imperfecta type IV
• type I procollagen

Background

The extensive family of COL gene products (collagens) is composed of several chain types, including fibril-forming interstitial collagens (types I, II, III and V) and basement membrane collagens (type IV), each type containing multiple isoforms. Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Several collagens also play a role in cell adhesion, important for maintaining normal tissue architecture and function.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for COL1A2 Antibody (NBP1-19699)(2)

Publications using NBP1-19699

• Turtoi A, Blomme A, Bianchi E et al. Accessibilome of Human Glioblastoma: Collagen-VI-alpha-1 Is a new Target and a Marker of Poor Outcome. J. Proteome Res. 2014-11-03 [PMID: 25325876] (IF/IHC, WB, Human)
• Veronesi E, Murgia A, Casselli A et al. Transportation Conditions for Prompt Use of Ex-vivo Expanded and Freshly Harvested Clinical Grade Bone Marrow MSC For Bone Regeneration. Tissue Eng Part C Methods 2013-07-11 [PMID: 23845029] (IHC-P, Human)

Bioinformatics

• Gene Symbol: COL1A2
• Entrez:
  • 1278(Human)
• Uniprot:
  • P08123(Human)