CLCN3 Antibody (S258-5) [Alexa Fluor® 700]

• Reactivity: Hu, Mu, Rt
• Applications: ICC/IF, IHC
• Clone: S258-5
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 700

CLCN3 Antibody (S258-5) [Alexa Fluor® 700] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: Synthetic peptide amino acids 98-115 (cytoplasmic N-terminus) of rat Clcn3
• Localization: Membrane , Endosome , Endosome membrane , Cytoplasmic Vesicle , Secretory Vesicle Membrane
• Specificity: Detects 90kDa. Does not cross-react with Clcn4 or Clcn5 (based on KO validation results).
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CLCN3
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NBP2-59379. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Alternate Names for CLCN3 Antibody (S258-5) [Alexa Fluor® 700]

• chloride channel 3
• Chloride channel protein 3
• Chloride transporter ClC-3
• CLC3
• ClC-3
• H(+)/Cl(-) exchange transporter 3

Background

CLCN3 mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to theacidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis.May play an important role in n

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CLCN3