cIAP-1/HIAP-2 Antibody

Images

 
Western Blot: cIAP-1/HIAP-2 Antibody [NB100-56889] - Analysis of c-IAP1 in 1) human HCT-116 and 2) mouse NIH 3T3 cell lysate using this antibody at 1:500 dilution.
Western Blot: cIAP-1/HIAP-2 Antibody [NB100-56889] - Detection of c-IAP1 in human lung cell lysate. using NB100-56889 at 2 ug/ml dilution

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

cIAP-1/HIAP-2 Antibody Summary

Immunogen
The antibody was developed by immunizing rabbits with a synthetic peptide corresponding to 361-372 of human c-IAP1
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
BIRC2
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1-2 ug/ml
Positive Control
Lung Lysate (NB820-59235)

Reactivity Notes

Cross reacts with Human and Mouse.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Whole antisera
Preservative
0.05% Sodium Azide
Purity
Unpurified

Alternate Names for cIAP-1/HIAP-2 Antibody

  • API1Hiap-2
  • apoptosis inhibitor 1
  • baculoviral IAP repeat containing 2
  • baculoviral IAP repeat-containing 2
  • baculoviral IAP repeat-containing protein 2
  • BIRC2
  • cIAP1
  • c-IAP1
  • cIAP-1
  • hIAP2
  • HIAP-2
  • IAP homolog B
  • IAP2
  • IAP-2
  • Inhibitor of apoptosis protein 2
  • MIHB
  • MIHBHIAP2
  • NFR2-TRAF signalling complex protein
  • RING finger protein 48
  • RNF48hiap-2
  • TNFR2-TRAF-signaling complex protein 2

Background

The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli. All IAPs have at least one baculovirus IAP repeat (BIR) motif that is essential for their anti-apoptotic activity. c-IAP1 and c-IAP2, that are closely related mammalian members of the inhibitor of apoptosis protein (IAP) family originally identified in baculoviruses.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Additional cIAP-1/HIAP-2 Products

Bioinformatics Tool for cIAP-1/HIAP-2 Antibody (NB100-56889)

Discover related pathways, diseases and genes to cIAP-1/HIAP-2 Antibody (NB100-56889). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for cIAP-1/HIAP-2 Antibody (NB100-56889)

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Research Areas for cIAP-1/HIAP-2 Antibody (NB100-56889)

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Blogs on cIAP-1/HIAP-2.

cIAP1 - An apoptotic regulator with implications in drug resistant cancers
Cellular inhibitor of apoptosis protein-1 (cIAP-1) is an anti-apoptotic protein that is able to bind to caspases and inhibit their activity. Additionally cIAP-1 contains a RING domain with E3 ubiquitin ligase activity that is able to mediate the r...  Read full blog post.

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Bioinformatics

Gene Symbol BIRC2
Entrez