Chitinase 3-like 1/YKL-40 Antibody (2C10)

Product Discontinued

Chitinase 3-like 1/YKL-40 Antibody (2C10) Summary

• Immunogen: Recombinant human CHI3L1 (22-383aa) purified from E. coli (NP_001267).
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: CHI3L1
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot 1:250-1:1500
• Theoretical MW: 43 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4), 10% Glycerol
• Preservative: 0.02% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Protein G purified

Alternate Names for Chitinase 3-like 1/YKL-40 Antibody (2C10)

• AW208766
• Brp39
• CHI3L1
• Chitinase 3 like 1
• Chitinase 3-like 1
• gp39
• HCgp39
• YKL-40

Background

Chitinase 3-Like-1 (CHI3L1) is a recently discovered human glycoprotein which is related in amino acid sequence to the chitinase protein family, but has no chitinase activity. CHI3L1 is upregulated in a number of cancers and in non-neoplatic disease states characterized by chronic inflammation and tissue remodeling. Its pattern of expression is associated with pathogenic processes related to inflammation, extracellular tissue remodeling, fibrosis and solid carcinomas. CHI3L1 may play an important role in the capacity of cells to respond to and cope with changes in their environment.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CHI3L1
• Entrez:
  • 1116(Human)
• Uniprot:
  • P36222()