Centaurin alpha 1 Antibody

Images

 
Western Blot: Centaurin alpha 1 Antibody [NBP1-31179] - Sample(30 ug of whole cell lysate)A: A431 B: HeLaS3 7. 5% SDS PAGE, antibody diluted at 1:500.
Immunohistochemistry-Paraffin: Centaurin alpha 1 Antibody [NBP1-31179] - Paraffin-embedded gastric tissue, using antibody at 1:100 dilution.
Western Blot: Centaurin alpha 1 Antibody [NBP1-31179] - A: 293T B :H1299 7.5% SDS PAGE; antibody diluted at 1:500

Product Details

Summary
Reactivity Hu, Mu, Rt, Po, BvSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.44 mg/ml

Order Details

Centaurin alpha 1 Antibody Summary

Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Centaurin alpha 1. The exact sequence is proprietary.
Localization
Nucleus, Cytoplasm
Predicted Species
Mouse (100%), Rat (100%), Porcine (100%), Bovine (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ADAP1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunohistochemistry 10 - 1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
Preservative
0.01% Thimerosal
Concentration
0.44 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Centaurin alpha 1 Antibody

  • arf-GAP with dual PH domain-containing protein 1
  • ArfGAP with dual PH domains 1
  • CENTA1centaurin-alpha-1
  • centaurin, alpha 1
  • centaurin-alpha
  • Centaurin-alpha-1
  • cnt-a1
  • GCS1L
  • p42IP4
  • Putative MAPK-activating protein PM25

Background

The centaurin alpha 1 protein is a high affinity PtdIns(3,4,5)P3 binding protein enriched in brain. By acting as a GTPase activating protein for ADP ribosylation factor 6 (ARF6), centaurin alpha 1 is able to switch off ARF6 and inhibit its ability to mediate beta 2 adrenoceptor internalization and negatively regulates ARF6 activity by functioning as an in vivo PIP3 dependent ARF6 GAP.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol ADAP1