Centaurin alpha 2 Antibody

Immunohistochemistry-Paraffin: Centaurin alpha 2 Antibody [NB100-1319] - (5ug/ml) staining of paraffin embedded Human Placenta. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

• Reactivity: Hu
• Applications: ELISA, IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

Centaurin alpha 2 Antibody Summary

• Immunogen: Peptide with sequence C-RLTASTESGRSSR corresponding to C-Terminus according to NP_060874.1.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: ADAP2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 5 - 10 ug/ml
  • Immunohistochemistry-Paraffin 5 - 10 ug/ml
  • Peptide ELISA Detection limit 1:32000
• Application Notes: WB: Preliminary experiments in human brain and heart lysates gave no specific signal but low background. IHC-P: Human placenta shows trong staining of cytoplasm in syncytiotrophoblasts.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Centaurin alpha 2 Antibody

• arf-GAP with dual PH domain-containing protein 2
• ArfGAP with dual PH domains 2
• CENTA2centaurin-alpha 2 protein
• centaurin beta
• centaurin, alpha 2
• centaurin-alpha-2
• cent-b
• cnt-a2
• HSA272195

Background

Centaurin alpha 2 is a potential GTPase-activating protein for the ADP ribosylation factor family. It binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4). It possesses a stoichiometry of two binding sites for InsP4 with identical affinity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Centaurin alpha 2 Antibody (NB100-1319)(1)

Publication using NB100-1319

• Jenne DE, Tinschert S, Stegmann E et al. A common set of at least 11 functional genes is lost in the majority of NF1 patients with gross deletions. Genomics 2000-05-15 [PMID: 10843809]

Bioinformatics

• Gene Symbol: ADAP2
• Entrez:
  • 55803(Human)
• Uniprot:
  • NP_060874.(Human)