CDC73/HRPT2 Antibody - BSA Free

Western Blot: CDC73/HRPT2 Antibody [NBP2-59257] - Western blot was performed on whole cell extracts (WCE) from drosophila larva and drosophila adults (Figure A) or on nuclear extracts from HeLa cells (HeLa NE, 20 ug) (Figure B) using the antibody against dCdc73 diluted 1:1,000 in TBS-Tween containing 5% skimmed milk. A molecular weight marker (kDa) is shown on the left; the location of the protein of interest is indicated on the right.

• Reactivity: Hu, Dr
• Applications: WB, ChIP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

CDC73/HRPT2 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit CDC73/HRPT2 Antibody - BSA Free (NBP2-59257) is a polyclonal antibody validated for use in WB and ChIP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: The exact immunogen is propietary information.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CDC73
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Chromatin Immunoprecipitation (ChIP) 1-5 ug/IP
  • Western Blot 1:1000

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide and 0.05% ProClin 300
• Purity: Protein G purified

Alternate Names for CDC73/HRPT2 Antibody - BSA Free

• C1orf28hyperparathyroidism 2 (with jaw tumor)
• CDC73
• cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S.cerevisiae)
• Cell division cycle protein 73 homolog
• chromosome 1 open reading frame 28
• HPTJT
• HPT-JT
• HRPT2
• HRPT2FLJ23316
• Hyperparathyroidism 2 protein
• HYX
• Parafibromin

Background

Parafibromin, the product of gene HPRT2, acts as a tumor suppressor protein by inhibiting cell proliferation and blocking expression of cyclin D1 when overexpressed. Parafibromin has also been shown to bind with the PAF1 complex / RNA polymerase II which is involved with transcription elongation and the RNA processing pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CDC73