CDC73/HRPT2 Products

Description

Parafibromin, the product of gene HPRT2, acts as a tumor suppressor protein by inhibiting cell proliferation and blocking expression of cyclin D1 when overexpressed. Parafibromin has also been shown to bind with the PAF1 complex / RNA polymerase II which is involved with transcription elongation and the RNA processing pathway.

Bioinformatics

Entrez	79577 Human
Uniprot	NM_024529 Human NP_078805.3 Human Q6P1J9 (human) Human Q6P1J9 Human
Product By Gene ID	79577
Alternate Names	C1orf28hyperparathyroidism 2 (with jaw tumor) cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S.cerevisiae) Cell division cycle protein 73 homolog chromosome 1 open reading frame 28 HPTJT HRPT2FLJ23316 Hyperparathyroidism 2 protein HYX parafibromin

Research Areas for CDC73/HRPT2

Find related products by research area and learn more about each of the different research areas below.

Cancer
Tumor Suppressors