Species: Hu, Mu, Rt
Applications: WB, IP
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: WB
Host: Goat Polyclonal
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Rabbit Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
Parafibromin, the product of gene HPRT2, acts as a tumor suppressor protein by inhibiting cell proliferation and blocking expression of cyclin D1 when overexpressed. Parafibromin has also been shown to bind with the PAF1 complex / RNA polymerase II which is involved with transcription elongation and the RNA processing pathway.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
79577 |
| Alternate Names |
- C1orf28hyperparathyroidism 2 (with jaw tumor)
- cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S.cerevisiae)
- Cell division cycle protein 73 homolog
- chromosome 1 open reading frame 28
- HPTJT
- HRPT2FLJ23316
- Hyperparathyroidism 2 protein
- HYX
- parafibromin
|
Research Areas for CDC73/HRPT2
Find related products by research area and learn more about each of the different research areas below.
CancerTumor Suppressors
