CDC73/HRPT2 Antibody (23GB3450)

• Reactivity: Hu, Mu, Rt
• Applications: WB, Flow, ICC/IF, Mycoplasma
• Clone: 23GB3450
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated

CDC73/HRPT2 Antibody (23GB3450) Summary

• Immunogen: A synthesized peptide derived from human HRPT2 / CDC73/HRPT2 (Uniprot: Q6P1J9)
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: CDC73
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Knockdown Validated
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4), 50% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for CDC73/HRPT2 Antibody (23GB3450)

• C1orf28hyperparathyroidism 2 (with jaw tumor)
• CDC73
• cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S.cerevisiae)
• Cell division cycle protein 73 homolog
• chromosome 1 open reading frame 28
• HPTJT
• HPT-JT
• HRPT2
• HRPT2FLJ23316
• Hyperparathyroidism 2 protein
• HYX
• Parafibromin

Background

Parafibromin, the product of gene HPRT2, acts as a tumor suppressor protein by inhibiting cell proliferation and blocking expression of cyclin D1 when overexpressed. Parafibromin has also been shown to bind with the PAF1 complex / RNA polymerase II which is involved with transcription elongation and the RNA processing pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CDC73