CDC42 Antibody - BSA Free

Western Blot: CDC42 Antibody [NBP1-76330] - Human brain tissue lysate with CDC42 antibody at (A) 0.5 and (B) 1 ug/ml.

• Reactivity: Hu, Mu, Rt, Po, Bv, Ch, Gp
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Chicken
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

CDC42 Antibody - BSA Free Summary

• Description: Novus Biologicals Chicken CDC42 Antibody - BSA Free (NBP1-76330) is a polyclonal antibody validated for use in WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human CDC42. The immunogen is located within amino acids 40 - 90 of CDC42. Amino Acid Squence: FDTAGQEDYDRLRPLSY
• Predicted Species: Porcine (100%), Bovine (100%), Guinea Pig (100%), Chicken (100%). Backed by our 100% Guarantee.
• Isotype: IgY
• Clonality: Polyclonal
• Host: Chicken
• Gene: CDC42
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot 0.5-1 ug/ml
• Control Peptide:

  CDC42 Protein (NBP1-76330PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Notes

Chicken products cannot be exported to Canada.

Alternate Names for CDC42 Antibody - BSA Free

• CDC42
• CDC42Hs
• cell division control protein 42 homolog
• cell division cycle 42 (GTP binding protein, 25kDa)
• cell division cycle 42 (GTP-binding protein, 25kD)
• dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD))
• dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD))
• G25K GTP-binding protein
• G25K
• growth-regulating protein
• GTP-binding protein, 25kD
• small GTP binding protein CDC42

Background

CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to S. cerevisiae CDC42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. CDC42 is thought to regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. At least two isoforms of CDC42 are known to exist.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CDC42
• Uniprot:
  • NP_001782(Human)