CD81 Antibody (2F7) - Azide and BSA Free

Images

 
Flow Cytometry: CD81 Antibody (2F7) [NBP1-28136] - Chinese hamster ovary cell line CHO-K1 and BALB/cAnN mouse B lymphocyte cell line A20 were stained with Hamster Anti-Mouse CD81-APC.
Flow Cytometry: CD81 Antibody (2F7) [NBP1-28136] - 0.1 ug/1^6 The A20 cell line, a murine B cell lymphoma, was stained with hamster anti-mouse CD81-R: PE or hamster IgG-R: PE isotype control, following which the cells ...read more
Flow Cytometry: CD81 Antibody (2F7) [NBP1-28136] - Analysis using the FITC conjugate of NBP1-28136. Staining of CHO-K1 cell line (Gray) and BALB/CAnN B lymphocyte cell line A20 (Purple).

Product Details

Summary
Reactivity Hu, Mu, HaSpecies Glossary
Applications Flow
Clone
2F7
Clonality
Monoclonal
Host
Armenian Hamster
Conjugate
Unconjugated
Format
Azide and BSA Free
Concentration
0.5 mg/ml

CD81 Antibody (2F7) - Azide and BSA Free Summary

Immunogen
Mouse epithelial cell line PAM212
Specificity
Mouse CD81 (Mr 25 kDa), a member of the transmembrane 4 integral membrane protein family
Isotype
IgG3
Clonality
Monoclonal
Host
Armenian Hamster
Gene
CD81
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10 - 1:1000
Publications
Read Publication using NBP1-28136.

Reactivity Notes

Human reactivty reported in (PMID:23260141).

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
0.1M BBS (pH 8.2)
Preservative
No Preservative
Concentration
0.5 mg/ml
Purity
Protein A or G purified

Alternate Names for CD81 Antibody (2F7) - Azide and BSA Free

  • CD81 antigen (target of antiproliferative 1)
  • CD81 antigen
  • CD81 molecule
  • CD81
  • CVID6
  • TAPA1
  • TAPA-1
  • Target of the antiproliferative 1
  • Tetraspanin-28
  • TSPAN28
  • Tspan-28
  • tspan-28,26 kDa cell surface protein TAPA-1
  • TSPAN28S5.7

Background

CD81/ TAPA-1 is an integral membrane protein expressed on a variety of cell types and has a high degree of sequence homology between human and mouse. CD81 is expressed on thymic stromal cells where it plays an important role in the transition of gamma-delta +T cells to more mature T cells with alpha-beta T cell receptors. Immunohistochemical staining has revealed that its expression is localized to the subcapsular region of the thymus and, specifically, on cells that have distinct clustering patterns. It has been speculated that the ligand for CD81 is the pre-T cell receptor which is composed of a TCR beta chain and glycoprotein pT alpha. The monoclonal antibody 2F7 can block thymocyte interaction with CD81 in vitro.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CD81 Antibody (NBP1-28136)(1)

We have publications tested in 1 confirmed species: Human.


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Secondary Antibodies

 

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Blogs on CD81.

Glypican 3 as a biomarker for gastro-esophageal adenocarcinoma
By Jamshed Arslan, Pharm. D., PhD. Gastroesophageal adenocarcinoma originates from the glandular epithelium of the esophagus, gastroesophageal junction and stomach. The incidence of gastroesophageal adenocarcinoma is ...  Read full blog post.

Tools for Isolation, Quantification and Analysis of Exosomes
Exosomes are spherical to cup-shaped bilayered membrane enclosed nanosize vesicles (30-100 nm) which have the ability to shuttle active cargoes between cells. Johnstone et al. 1987 pioneered in documenting the generation of exosomes in differentiat...  Read full blog post.

CD19: An Undoubted Biomarker for B Cells
CD19 is a cell surface protein member of the large immunoglobulin superfamily that complexes with CD21, CD81, and CD225 in the membrane of mature B-cells. A major function of CD19 is to assemble with the antigen receptor of B-lymphocytes to decrease t...  Read full blog post.

CD81/TAPA1: I'm on Tapa the Cell
Target of the antiproliferative 1 (TAPA1), also known as CD81, is found in the plasma membrane in lymphocytes and plays an important role in the regulation of lymphoma cell growth. This transmembrane 4 superfamily (TM4SF) protein is primarily found on...  Read full blog post.

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Bioinformatics

Gene Symbol CD81