CD79A Antibody (HM57) [DyLight 350]

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Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Bv, Ca, Ch, Eq, Ft, GP, Gt, Mk, RbSpecies Glossary
Applications Flow, ICC/IF, IHC-Fr, IHC-P
Clone
HM57
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 350

CD79A Antibody (HM57) [DyLight 350] Summary

Immunogen
Synthetic peptide corresponding to 202-216 amino acid sequence of human mb-1.
Specificity
NB100-64347 recognizes an epitope within the cytoplasmic domain of CD79a. CD79a, also known as mb-1, is a 45kD protein that is expressed by B lymphocytes during differentiation from early pre-B cell stage through to plasma cells. The CD79a molecule associates with CD79b (B29) to form a heterodimer that is non-covalently linked to surface immunoglobulin, forming the B-cell receptor (BCR) complex. The CD79a/CD79b heterodimers are also necessary for intracellular signalling following antigen-binding to surface immunoglobulin. Clone HM57 has been reported to work in western blotting applications.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CD79A
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin

Reactivity Notes

Cross reacts with Red Deer, Fallow Deer and American Bison. Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CD79A Antibody (HM57) [DyLight 350]

  • CD79A antigen (immunoglobulin-associated alpha)
  • CD79a antigen
  • CD79a molecule, immunoglobulin-associated alpha
  • CD79A
  • IGAB-cell antigen receptor complex-associated protein alpha chain
  • ig-alpha
  • MB-1 membrane glycoprotein
  • MB1
  • MB-1
  • Membrane-bound immunoglobulin-associated protein
  • Surface IgM-associated protein

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

FAQs for CD79A Antibody (NB100-64347UV) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Allophycocyanin Labeled NB100-64347APC
DyLight 405 Labeled NB100-64347V
DyLight 488 Labeled NB100-64347G
DyLight 680 Labeled NB100-64347FR
DyLight 755 Labeled NB100-64347IR
PE Labeled NB100-64347PE
PerCP Labeled NB100-64347PCP

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Bioinformatics Tool for CD79A Antibody (NB100-64347UV)

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Blogs on CD79A.

CD79b - A Signal Transduction Component of the B-cell Receptor
The B-cell antigen receptor (BCR) is a complex multimeric aggregate that includes the following key noncovalently-bound components: antigen-specific surface immunoglobulin (Ig), CD79a (Ig-alpha), and CD79b (Ig-beta). BCR signaling is a pivotal pathway...  Read full blog post.

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Bioinformatics

Gene Symbol CD79A
Entrez