CD46 Antibody (3F1) Summary
Recombinant CD46 protein
Monoclonal antibody reacts specifically with 44 kDa protein. Diffuse and duplicated bands can be seen due to the glycosylation of CD46.
Protein A or G purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Protein A or G purified
Reconstitute with 0.1 ml distilled water.
- Western Blot 1:100-1:2000
- ELISA 1:100-1:2000
- Immunohistochemistry 1:10-1:500
- Immunohistochemistry-Paraffin 1:10-1:500
Alternate Names for CD46 Antibody (3F1)
- CD46 antigen
- CD46 molecule, complement regulatory protein
- membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen)
- TLXcomplement regulatory protein
- trophoblast leucocyte common antigen
- Trophoblast leukocyte common antigen
- trophoblast-lymphocyte cross-reactive antigen
CD46 (MCP, membrane cofactor protein) is a multifunctional cell surface transmembrane protein that binds and inactivates C3b and C4b complement fragments, regulates T cell-induced inflammatory responses by either inhibiting (CD46-1 isoform) or increasing (CD46-2 isoform) the contact hypersensitivity reaction. CD46 also serves as a receptor for several human pathogens (both bacteria and viruses), and its ligation alteres T lymphocyte polarization toward antigen-presenting cells or target cells, inhibiting lymphocyte function. CD46 is a protector of placental tissue and is also expressed on the inner acrosomal membrane of spermatozoa.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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