CD46 Products

Description

CD46 is one of the membrane complement regulatory proteins. CD46 possesses C3b-binding and factor I cofactor activities which play important roles in regulation of complement activation pathway. CD46 is widely distributed on blood cells, endothelial cells, epithelial cells and tumor cell lines. CD46 exists as many isoforms in a variety of tissues. The antigen has a broad distribution and is present on leukocytes, platelets, endothelial cells, epithelial cells and fibroblasts. It is strongly expressed on salivary gland ducts and kidney ducts, moderately on lymphocytes and endothelium, and weakly on interstitial tissues and muscle cells, but not on erythrocytes. It is expressed on thymocytes, B cells, monocytes, granulocytes, NK cells, platelets, epithelial and endothelial cells.

Bioinformatics

Entrez	4179 Human
Uniprot	AAH30594 Human AAH30594.1 Human NM_002389 Human NP_722548.1 Human NP_758861 Human P15529 Human
Product By Gene ID	4179
Alternate Names	AHUS2 CD46 antigen CD46 molecule, complement regulatory protein membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen) MIC10 TLXcomplement regulatory protein trophoblast leucocyte common antigen Trophoblast leukocyte common antigen trophoblast-lymphocyte cross-reactive antigen

Research Areas for CD46

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cell Biology
Cellular Markers
Immunology