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CD37 Antibody (G28-1) - Chimeric - Azide and BSA Free

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Immunocytochemistry/ Immunofluorescence: CD37 Antibody (G28-1) - Chimeric [NBP3-09052] - Immunofluorescence analysis of paraformaldehyde fixed Daudi cells on Shi-fix(TM) coverslips stained with the chimeric rabbit IgG ...read more
Flow Cytometry: CD37 Antibody (G28-1) - Chimeric [NBP3-09052] - Analysis of Daudi cells

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, ICC/IF
Clone
G28-1
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated
Format
Azide and BSA Free
Concentration
1 mg/ml

Order Details

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Catalog# & Formulation Size Price

CD37 Antibody (G28-1) - Chimeric - Azide and BSA Free Summary

Additional Information
Recombinant Monoclonal Antibody. Clone G28-1 was used by HLDA to establish CD designation.
Immunogen
This antibody was raised by immunizing mice with CD37.
Isotype
IgG Kappa
Clonality
Monoclonal
Host
Rabbit
Gene
CD37
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
Application Notes
This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

G28-1 antibody was used to deplete normal and malignant B cells (Hayden-Ledbetter, unpublishesd). This antibody and antibody fragments derived therefrom have been used in the research and trials on the generation of novel immunotherapuetic agents, alternative to anti-CD20 therpaies (rituximab) (Robak and Robak, 2014).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Proclin 300
Concentration
1 mg/ml
Purity
Protein A purified

Alternate Names for CD37 Antibody (G28-1) - Chimeric - Azide and BSA Free

  • CD37 antigentetraspanin-26
  • CD37 molecule
  • CD37
  • cell differentiation antigen 37
  • GP52-40
  • leukocyte antigen CD37
  • MGC120234
  • Tetraspanin-26
  • TSPAN26
  • tspan-26
  • TSPAN26leukocyte surface antigen CD37

Background

CD37, also known as GP52-40, TSPAN26, MGC120234. Enterz Protein NP_001035120. It is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CD37