CD28 Antibody (37.51)


There are currently no images for CD28 Antibody (NBP1-30418).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Reactivity MuSpecies Glossary
Applications Flow, Func, ICC/IF, IHC, IHC-Fr, IP
Golden Syrian Hamster
1.0 mg/ml

CD28 Antibody (37.51) Summary

Mouse T cell lymphoma EL-4 cells
The Syrian hamster monoclonal antibody 37.51 reacts with extracellular domain of mouse CD28 costimulatory receptor, a 45 kDa homodimeric protein expressed by thymocytes, mature T cells and NK cells.
Golden Syrian Hamster
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Store at 4C. Do not freeze.
PBS [pH 7.4] (0.2 um filter sterilized) Endotoxin level is less than 0.1 EU/mg of the protein, as determined by the LAL test.
No Preservative
1.0 mg/ml
Protein G purified


  • Flow Cytometry 6 ug/ml
  • Functional
  • Immunocytochemistry/Immunofluorescence 1 - 4 ug/ml
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:200
  • Immunoprecipitation 1-2 ug / 100-500 ug of protein in 1 ml lysate
Application Notes
Functional Application: In vitro and in vivo T cell costimulation

Alternate Names for CD28 Antibody (37.51)

  • CD28 antigen (Tp44)
  • CD28 antigen
  • CD28 molecule
  • CD28
  • MGC138290
  • T-cell-specific surface glycoprotein CD28
  • Tp44


CD28 is the critical T cell costimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its costimulation role CD28 functions in preventing T cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. In murine peripheral lymphoid organs and in the blood, all CD4+ and CD8+ T cells express CD28. In the thymus, CD28 expression is highest on immature CD3-, CD8+ and CD4+8+ cells, and on CD4-8- cells that express alpha/beta and gamma/delta TCR. The level of CD28 on mature CD4+ and CD8+ alpha/beta TCR+ thymocytes is two- to fourfold lower than on the immature cells.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P, IP
Species: Hu
Applications: Flow, Func, In vitro, In vivo, Flow-CS
Species: Hu, Mu, Rt, Ca, Rb
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
Species: Mu, Rt
Applications: Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, Cell Depl, InhibTFunc
Species: Hu
Applications: WB, ELISA, ICC/IF, S-ELISA
Species: Hu
Applications: WB, AgAct
Species: Hu
Applications: WB, B/N, Flow, IHC, IHC-Fr
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Species: Mu
Applications: Flow, Func, ICC/IF, IHC, IHC-Fr, IP

Publications for CD28 Antibody (NBP1-30418) (0)

There are no publications for CD28 Antibody (NBP1-30418).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for CD28 Antibody (NBP1-30418) (0)

There are no reviews for CD28 Antibody (NBP1-30418). By submitting a review earn points towards our Rewards Program.
  • 250 points for product review
  • 500 additional points for an image with your product review
  • Double points (500) if you are the first to review this product
  • Double points (1000) if you are the first to review this product with an image

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

ICC/IF Video Protocol

FAQs for CD28 Antibody (NBP1-30418) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies


Isotype Controls

Other Available Formats

PE/Cy5 Labeled NBP2-00100
PE/Cy7 Labeled NBP1-99999
PerCP/Cy5.5 Labeled NBP2-00098

Additional CD28 Antibody (37.51) Products

Related Products by Gene

Bioinformatics Tool for CD28 Antibody (NBP1-30418)

Discover related pathways, diseases and genes to CD28 Antibody (NBP1-30418). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for CD28 Antibody (NBP1-30418)

Discover more about diseases related to CD28 Antibody (NBP1-30418).

Pathways for CD28 Antibody (NBP1-30418)

View related products by pathway.

PTMs for CD28 Antibody (NBP1-30418)

Learn more about PTMs related to CD28 Antibody (NBP1-30418).

Research Areas for CD28 Antibody (NBP1-30418)

Find related products by research area.

Blogs on CD28.

CD80: A co-stimulator of T cell activation
CD80 is a 60kD single chain type I transmembrane glycoprotein that is a member of the immunoglobulin family. CD80 is expressed on activated B- and T-lymphocytes, as well as a subpopulation of previously activated B-cells, but not on the majority of re...  Read full blog post.

Contact Information

Product PDFs


Gene Symbol CD28

Customer Resources

Novus Review - Submit your review and earn rewards points which can be used for merchandise & discounts.
Risk Free Testing - Test on a species/application not listed above to receive a full credit towards a future purchase.

Novus' Quality Guarantee - Novus guarantees that every product we sell will work in the application and species listed on our website and datasheets.

Submit your question on NBP1-30418 below.
During business hours, we will respond to your email within 24 hours. For any questions submitted on the weekend, a response will be received on Monday.
For immediate assistance during business hours M- F (excluding major holidays), please contact us.
Ask a Scientist - We have a lab full of white coats just waiting for your scientific questions and concerns.

Customers Who Bought This Also Bought

CD28 Recombinant Protein