CD28 Products

Antibodies
CD28 Antibody (37407) [Unconj ...
CD28 Antibody (37407) [Unconjugated]
MAB342
Species: Hu
Applications: WB, Flow, AgAct
Host: Mouse Monoclonal
CD28 Antibody
CD28 Antibody
AF-342-PB
Species: Hu
Applications: WB, Flow, AgAct, ICC
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
CD28 Antibody (61109)
CD28 Antibody (61109)
MAB4831
Species: Mu
Applications: WB
Host: Rat Monoclonal
Antibody Pairs
CD28 Antibody Pair
CD28 Antibody Pair
H00000940-AP41
Species: Hu
Applications: S-ELISA
ELISA Kits
CD28 ELISA Kit [Biotin]
CD28 ELISA Kit [Biotin]
NBP1-91279
Applications: ELISA
Lysates
CD28 Overexpression Lysate (D ...
CD28 Overexpression Lysate (Denatu...
H00000940-T01
Species: Hu
Applications: WB
CD28 Overexpression Lysate (N ...
CD28 Overexpression Lysate (Native)
NBP2-04308
Applications: WB
Proteins
CD28 Recombinant Protein
CD28 Recombinant Protein
H00000940-G01
Species: Hu
CD28 Recombinant Protein
CD28 Recombinant Protein
H00000940-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
CD28 RNAi
CD28 RNAi
H00000940-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

CD28 is the critical T cell costimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its costimulation role CD28 functions in preventing T cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. In murine peripheral lymphoid organs and in the blood, all CD4+ and CD8+ T cells express CD28. In the thymus, CD28 expression is highest on immature CD3-, CD8+ and CD4+8+ cells, and on CD4-8- cells that express alpha/beta and gamma/delta TCR. The level of CD28 on mature CD4+ and CD8+ alpha/beta TCR+ thymocytes is two- to fourfold lower than on the immature cells.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Mouse
Product By Gene ID 940
Alternate Names
  • TP44
  • MGC138290
  • T-cell-specific surface glycoprotein CD28
  • CD28 antigen (Tp44)
  • Tp44
  • CD28 antigen
  • CD28 molecule

Research Areas for CD28

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Apoptosis
CD Markers
Immunology

Bioinformatics Tool for CD28

Discover related pathways, diseases and genes to CD28. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related CD28 Blog Posts

Check out the latest blog posts on CD28.
CD80: A co-stimulator of T cell activation
CD80 is a 60kD single chain type I transmembrane glycoprotein that is a member of the immunoglobulin family. CD80 is expressed on activated B- and T-lymphocytes, as well as a subpopulation of previously activated B-cells, but not on the majority of re...    Read more.
Read more CD28 related blogs.