CD20 Antibody (Hu10F2) [Alexa Fluor® 750]

• Applications: Flow
• Clone: Hu10F2
• Clonality: Monoclonal
• Host: Human
• Conjugate: Alexa Fluor 750

CD20 Antibody (Hu10F2) [Alexa Fluor® 750] Summary

• Additional Information: Recombinant Monoclonal Antibody For Research Use Only
• Immunogen: Human MS4A1/CD20
• Specificity: Detects human CD20 in direct ELISAs.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Human
• Purity Statement: Protein A or G purified

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

CD20 is a 297 amino acid (aa) non-glycosylated type III membrane protein that is the founding member of the MS4A tetraspanin protein family. It is expressed on pre-B, naïve and mature B lymphocytes and B-cell lymphomas. CD20 is associated with lipid rafts upon crosslinking, and appears to play a role in regulation of ion influx. The one extracellular segment of 48 aa shows 65% aa sequence identity between human and mouse CD20.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.