CD2 Antibody (12-15) [PE]

Images

 
Flow Cytometry: CD2 Antibody (12-15) [PE] [NBP1-26669] - C57BL/6 mouse splenocytes stained with NBP1-26669 (PE conjugate) and NBP1-26667 (FITC conjugate)

Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, In vitro, IP
Clone
12-15
Clonality
Monoclonal
Host
Rat
Conjugate
PE
Concentration
0.1 mg/ml

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price

CD2 Antibody (12-15) [PE] Summary

Immunogen
Crude plasma membranes of ESb cells
Specificity
Mouse CD2/LFA-2 (Mr 45-58 kDa)
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Rat
Gene
CD2
Purity
Protein A or G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Flow Cytometry <= 0.5 ug/10^6 cells
  • Immunoprecipitation 1:10-1:500
  • In vitro assay
Application Notes
Flow Cytometry, Immunoprecipitation, In vitro inhibition of CTL-mediated lysis, Induction of T cell unresponsiveness in vivo

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS and a stabilizing agent
Preservative
Sodium Azide
Concentration
0.1 mg/ml
Purity
Protein A or G purified

Notes

Protect conjugated forms from light.

Alternate Names for CD2 Antibody (12-15) [PE]

  • CD2 antigen (p50), sheep red blood cell receptor
  • CD2 antigen
  • CD2 molecule
  • CD2
  • Erythrocyte receptor
  • FLJ46032
  • LFA-2
  • LFA-3 receptor
  • lymphocyte-function antigen-2
  • Rosette receptor
  • SRBC
  • T11
  • T-cell surface antigen CD2
  • T-cell surface antigen T11/Leu-5

Background

CD2 is a surface antigen of the human T lymphocyte lineage that is expressed on all peripheral blood T cells. It is one of the earliest T cell markers, being present on more than 95% of thymocytes; it is also found on some natural killer cells but not on B lymphocytes. CD2 interacts with lymphocyte function associated antigen (LFA3) and CD48/BCM1 to mediate adhesion between T cells and other cell types. CD2 is implicated in the triggering of T cells, the cytoplasmic domain is implicated in the signaling function. It is useful for the identification of lymphomas and leukaemias of T cell origin.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs for CD2 Antibody (NBP1-26669) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Biotin Labeled NBP1-26668
FITC Labeled NBP1-26667

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Bioinformatics

Gene Symbol CD2
Entrez