CD1b Antibody (CC20) [Janelia Fluor® 646]

• Reactivity: Bv
• Applications: Flow, IHC, IP
• Clone: CC20
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 646

CD1b Antibody (CC20) [Janelia Fluor® 646] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: Made to Bovine CD1w2
• Specificity: Recognizes the bovine CD1w2 cell surface antigen, a glycoprotein heterodimer of 12kD and 46kD. CD1w2 is expressed by cortical thymocytes and a minority of medullary thymocytes, with a pattern similar to antibodies of the CD1b cluster in humans.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: CD1B
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunoprecipitation
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NB100-65315. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Reactivity Notes

Predicted cross-reactivities: Sheep, Equine, Goat, Dog, Feline

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for CD1b Antibody (CC20) [Janelia Fluor® 646]

• CD1
• CD1A
• CD1b antigen
• CD1B antigen, b polypeptide
• CD1b molecule
• CD1b
• cortical thymocyte antigen CD1B
• differentiation antigen CD1-alpha-3
• MGC125990
• MGC125991
• R1
• T-cell surface glycoprotein CD1b

Background

All CD1 molecules, except CD1e, are cell surface glycoproteins that are structurally related to the MHC molecules, however, in distinction, CD1 proteins are essentially non polymorphic. CD1 has considerable structural homology with both MHC class I and class II molecules, and CD1 molecules are involved in T cell activation. In contrast to MHC, however, CD1 molecules appear to present predominantly non peptide molecules originating from lipids and glycolipids.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CD1B