CD155/PVR Antibody - BSA Free

Analysis in human placenta and tonsil tissues using HPA012568 antibody. Corresponding PVR RNA-seq data are presented for the same tissues.

Immunohistochemistry-Paraffin: CD155/PVR Antibody [NBP1-88131] - Staining of human placenta shows moderate membranous positivity in trophoblastic cells.

Immunohistochemistry-Paraffin: CD155/PVR Antibody [NBP1-88131] - Staining of human tonsil shows no positivity in lymphoid cells as expected.

Immunohistochemistry-Paraffin: CD155/PVR Antibody [NBP1-88131] - Staining of human prostate shows weak to moderate membranous positivity in glandular cells.

Immunohistochemistry-Paraffin: CD155/PVR Antibody [NBP1-88131] - Staining of human stomach shows moderate membranous positivity in glandular cells.

Analysis in human cell lines A-431 and MCF-7 using Anti-PVR antibody. Corresponding PVR RNA-seq data are presented for the same cell lines. Loading control: Anti-GAPDH.

• Reactivity: Hu
• Applications: WB, IHC, mIF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

CD155/PVR Antibody - BSA Free Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: DVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFP
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PVR
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
  • Multiplex Immunofluorescence
  • Western Blot 0.04 - 0.4 ug/ml
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  CD155/PVR Protein (NBP1-88131PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for CD155/PVR Antibody - BSA Free

• CD155 antigen
• CD155
• HVED
• NECL5
• Necl-5
• nectin-like 5
• Nectin-like protein 5
• poliovirus receptor
• PVR
• PVS
• PVSFLJ25946
• Tage4

Background

Polio Virus Receptor (PVR) is a member of Ig-superfamily with 3 Ig-domains in arrangement V-C-C. Four mRNAs are produced from single gene for PVR, (mapped to human chromosome band 19q13.1-13.2). Two of the mRNAs (called H20A and H20B or alpha and delta) encode cell surface molecules of about 43kDa and 45kDa polypeptide backbone, respectively. Two other splice variants, beta and gamma encode secreted molecules of about 44kDa. The cytoplasmic tails are short (aa 35-50) and are rich in serine phosphorylated residues.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CD155/PVR Antibody (NBP1-88131)(1)

Publication using NBP1-88131

• Peng YP, Xi CH, Zhu Y et al. Altered expression of CD226 and CD96 on natural killer cells in patients with pancreatic cancer. Oncotarget. 2016-10-11 [PMID: 27626490] (IF/IHC, Human)

Bioinformatics

• Gene Symbol: PVR