CCNDBP1 Antibody - BSA Free

Western Blot: CCNDBP1 Antibody [NBP2-15762] - Western Blot analysis of CCNDBP1 expression in transfected 293T cell line by CCNDBP1 polyclonal antibody. A: Non-transfected lysate. B: CCNDBP1 transfected lysate. 12% SDS PAGE gel, diluted at 1:500.

Immunohistochemistry-Paraffin: CCNDBP1 Antibody [NBP2-15762] - Immunohistochemical analysis of paraffin-embedded endo mitrial, using antibody at 1:100 dilution.

• Reactivity: Hu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

CCNDBP1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit CCNDBP1 Antibody - BSA Free (NBP2-15762) is a polyclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CCNDBP1. The exact sequence is proprietary.
• Localization: Cytoplasm; Nucleus
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CCNDBP1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 10 - 1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
• Theoretical MW: 40 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for CCNDBP1 Antibody - BSA Free

• cyclin D-type binding-protein 1
• cyclin-D1-binding protein 1
• DIP1HHM Protein
• D-type cyclin-interacting protein 1
• GCIPgrap2 cyclin interacting protein
• Grap2 and cyclin-D-interacting protein
• HHM
• Human homolog of Maid
• MAID protein

Background

This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Two alternatively spliced variants, which encode distinct isoforms, have been reported. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: CCNDBP1
• Uniprot:
  • O95273(Human)