CCNDBP1 Products

Description

CCNDBP1 was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Two alternatively spliced variants, which encode distinct isoforms, have been reported.

Bioinformatics

Entrez	23582 Human
Uniprot	AAH09689.1 Human NM_012142 Human NM_037370 Human NP_036274 Human O95273 Human
Product By Gene ID	23582
Alternate Names	cyclin D-type binding-protein 1 cyclin-D1-binding protein 1 DIP1HHM Protein D-type cyclin-interacting protein 1 GCIPgrap2 cyclin interacting protein Grap2 and cyclin-D-interacting protein HHM Human homolog of Maid MAID protein