Recombinant Human CCL3L1/LD78 beta Protein

• Reactivity: Hu
• Applications: PAGE, Bioactivity
• Format: Carrier-Free
• Concentration: LYOPH

Recombinant Human CCL3L1/LD78 beta Protein Summary

• Description: Approximately 7.8 kDa protein corresponding to 70 amino acid residues of CCL3L1/LD78 beta, including the four highly conserved cysteine residues present in CC chemokines Source: E. coli

  Uniprot ID: P16619

  Amino Acid Sequence: APLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPSV IFLTKRGRQV CADPSEEWVQ KYVSDLELSA

• Details of Functionality: CCL3L1 Protein is fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 1.0-10 ng/ml.
• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: CCL3L1
• Purity: > 97 % pure by SDS-PAGE and HPLC
• Endotoxin Note: Less than 1 EU/ug of CCL3L1/LD78 beta as determined by LAL method.

Applications/Dilutions

• Dilutions:
  • Bioactivity
  • SDS-Page
• Theoretical MW: 7.8 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20 to -70C as supplied. After reconstitution, store at 2 to 8C for 1 month and at -20 to -70C for long term storage. Avoid repeated freeze-thaw cycles.
• Buffer: Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: > 97 % pure by SDS-PAGE and HPLC
• Reconstitution Instructions: Recommended to centrifuge prior to opening. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/mL.

Alternate Names for Recombinant Human CCL3L1/LD78 beta Protein

• C-C motif chemokine 3-like 1
• CCL3L3
• chemokine (C-C motif) ligand 3-like 1
• D17S1718
• G0/G1 switch regulatory protein 19-2
• G0S19-2LD78
• LD78BETA
• LD78-beta(1-70)
• MGC104178
• MGC12815
• MGC182017
• MIP1AP
• PAT 464.2
• SCYA3L
• SCYA3L1464.2
• small inducible cytokine A3-like 1
• Small-inducible cytokine A3-like 1
• Tonsillar lymphocyte LD78 beta protein

Background

CCL3L1, also named LD78-beta, is belonging to the intercrine beta (chemokine CC) family and it is encoded by the CCL3L1 gene in humans. This protein binds to several chemokine receptors including chemokine binding protein 2 (CCBP2 or D6) and chemokine (C-C motif) receptor 5 (CCR5). It is an inhibitor of HIV-1-infection and chemotactic for lymphocytes and monocytes. Recombinant human LD78beta is a 7.8 kDa protein containing 70 amino acid residues, including the four conserved cysteine residues present in CC chemokines.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: CCL3L1
• Uniprot:
  • P16619(Human)