Recombinant Human CCL13/MCP-4 Protein

Product Discontinued

Recombinant Human CCL13/MCP-4 Protein Summary

• Description: A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 24-98 of Human CCL13/MCP-4
  
  

  Source: E.coli

  Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MQPDALNVPS TCCFTFSSKK ISLQRLKSYV ITTSRCPQKA VIFRTKLGKE ICADPKEKWV QNYMKHLGRK AHTLKT

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: CCL13
• Purity: >90%, by SDS-PAGE
• Endotoxin Note: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 10.8 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4), 10% glycerol, 0.1 M NaCl, 1 mM DTT
• Preservative: No Preservative
• Concentration: 0.25 mg/ml
• Purity: >90%, by SDS-PAGE

Alternate Names for Recombinant Human CCL13/MCP-4 Protein

• C-C motif chemokine 13
• CCL13
• chemokine (C-C motif) ligand 13
• CKb10
• MCP4
• MCP-4
• MCP-4Monocyte chemoattractant protein 4
• MGC17134
• NCC-1Monocyte chemotactic protein 4
• NCC1Small-inducible cytokine A13
• new CC chemokine 1
• SCYA13CK-beta-10
• SCYL1
• small inducible cytokine subfamily A (Cys-Cys), member 13

Background

CCL13 is a small cytokine belonging to the CC chemokine family that is also known as thymus and activation regulated chemokine (TARC). This protein induces chemotaxis in monocytes, eosinophils, T lymphocytes, and basophils by binding cell surface G-protein linked chemokine receptors such as CCR2, CCR3 and CCR5. It can be induced by the inflammatory cytokines interleukin-1 and TNF-alpha. Recombinant human CCL13 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: CCL13