CBFA2T3 Antibody [mFluor Violet 450 SE]

• Reactivity: Hu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: mFluor Violet 450 SE

CBFA2T3 Antibody [mFluor Violet 450 SE] Summary

• Immunogen: C-terminus: between aa 603 and 653
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CBFA2T3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CBFA2T3 Antibody [mFluor Violet 450 SE]

• core-binding factor, runt domain, alpha subunit 2; translocated to, 3
• hMTG16
• MTG16ETO2
• MTG8-related protein 2
• MTGR2MTG8-related gene 2
• Myeloid translocation gene on chromosome 16 protein
• protein CBFA2T3
• Zinc finger MYND domain-containing protein 4
• ZMYND4myeloid translocation gene 8 and 16b

Background

The t(16;21)(q24;q22) translocation is a rare but recurrent chromosomal abnormality associated with therapy-related myeloid malignancies. The translocation produces a chimeric gene made up of the 5'-region of the AML1 gene fused to the 3'-region of this gene. In addition, this gene is a putative breast tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene, and a brefeldin A-sensitive association of RII-alpha protein with one of the isoforms has been demonstrated in the Golgi apparatus. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CBFA2T3