Caveolin-2 Antibody [Alexa Fluor™ Plus 555]

• Reactivity: Hu, Mu, Rt
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor Plus 555

Caveolin-2 Antibody [Alexa Fluor™ Plus 555] Summary

• Specificity: Detects endogenous human, mouse, and rat Caveolin-2 in Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Caveolin-2 Antibody [Alexa Fluor™ Plus 555]

• CAV
• CAV2
• caveolae protein, 20-kD
• caveolin 2 isoform a and b
• caveolin 2
• Caveolin2
• Caveolin-2
• MGC12294

Background

Caveolin-2 is a cell membrane-associated member of the caveolin family of proteins. Although its predicted MW is 17 kDa, it runs anomalously at 21‑22 kDa on SDS‑PAGE. Caveolin-2 is not ubiquitous, but it is found in divergent cell types such as smooth muscle, endothelial, and skeletal muscle cells, plus fibroblasts and adipocytes. When expressed alone, Caveolin-2 forms monomers and homodimers; when expressed with Caveolin-1, it exists as part of a 150 kDa, Caveolin-1 associated oligomeric complex. Human Caveolin-2 is 162 amino acids (aa) in length. It contains a central membrane-embedded sequence (aa 87‑107) flanked by two cytoplasmic domains (aa 1‑86 and 108‑162). Caveolin-2 has been found phosphorylated at tyrosines 19 and 27, and at serines 20, 23 and 36.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.