Caspase-4 Assay Kit (Fluorometric)

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      KA0747
    • Availability
      Product Discontinued

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Caspase-4 Assay Kit (Fluorometric) Summary

Description
Caspase-4 Inhibitor Screening Kit is used for screening caspase inhibitors using fluorometric methods.
Kit Type
Assay Kit (Fluorometric)
Gene
CASP4

Applications/Dilutions

Dilutions
  • Functional
Publications
Read Publication using KA0747.

Packaging, Storage & Formulations

Storage
Store at -20C.

Kit Components

Components
  1. 2X Reaction Buffer
  2. Active Caspase-4 (Lyophilized)
  3. Caspase Inhibitor, Z-VAD-FMK (2 mM)
  4. Caspase Substrate LEVD-AFC (1 mM)
  5. DTT (1 M)

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Caspase-4 Assay Kit (Fluorometric)

  • apoptotic cysteine protease Mih1/TX
  • CASP4
  • CASP-4
  • caspase 4, apoptosis-related cysteine peptidase
  • caspase 4, apoptosis-related cysteine protease
  • Caspase4
  • Caspase-4
  • EC 3.4.22
  • EC 3.4.22.57
  • ICE(rel)II
  • ICE(rel)-II
  • ICEREL-II
  • ICH2
  • ICH-2
  • Mih1/TX
  • Protease ICH-2
  • Protease TX
  • TX

Background

Caspase-4 Inhibitor Screening Kit is used for screening caspase inhibitors using fluorometric methods.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Kits are guaranteed for 6 months from date of receipt.

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Publications for Caspase-4 Kit (KA0747)(1)


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Research Areas for Caspase-4 Kit (KA0747)

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The NLRP3 Inflammasome: Macrophage Activator & Pathology Driver
By Victoria Osinski, PhDWhat is the NLRP3 Inflammasome?With its critical role in innate immunity, the nucleotide-binding oligomerization domain-like receptor family, pyrin domain containing 3 (NLRP3) inflammasome ...  Read full blog post.

Pyroptosis: Mechanisms mediating cell death and pro-inflammatory cytokine release
By Victoria OsinskiPyroptosis is an inflammatory form of programmed cell death characterized by the release of pro-inflammatory cytokines IL-1 beta and IL-18.1,10 It is a process distinct from apoptosis and necrosis (T...  Read full blog post.

Caspase-4 - a human protease with roles in inflammation and immunity
Caspases are a family of cysteine-aspartic acid proteases that cleave caspase proenzymes as well as other protein substrates. Caspases are well known for their role in apoptosis, but they also play a significant role in other cellular processes inc...  Read full blog post.

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Bioinformatics

Gene Symbol CASP4