Calpain 6 Antibody

Images

 
Western Blot: Calpain 6 Antibody [NBP1-76937] - Rat lung tissue lysate with Calpain 6 antibody at (A) 0.5 and (B) 1 ug/ml.
Immunocytochemistry/ Immunofluorescence: Calpain 6 Antibody [NBP1-76937] - Calpain 6 in Human Lung cells with CAPN6 antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: Calpain 6 Antibody [NBP1-76937] - Human lung tissue with Calpain 6 antibody at 2.5 ug/ml.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

Calpain 6 Antibody Summary

Immunogen
Antibody was raised against a 18 amino acid synthetic peptide from near the carboxy terminus of human CAPN6. The immunogen is located within the last 50 amino acids of CAPN6.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CAPN6
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 20 ug/ml
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Control Peptide
Calpain 6 Peptide (NBP1-76937PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Calpain 6 Antibody

  • calpain 6
  • calpain-6
  • Calpain-like protease X-linked
  • Calpamodulin
  • CalpMCALPM
  • CANPXcalpamodulin
  • CAPNX
  • DJ914P14.1
  • EC 3.4.22

Background

Calpains make up a ubiquitously expressed, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. This large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes as their activation can be triggered by calcium influx and oxidative stress. Calpain 6 (CAPN6) is most similar to Calpain 5; the C-terminal region of CAPN6 lacks homology to the calmodulin-like domain of other vertebrate calpains. CAPN6 is thought to be involved in the regulation of microtubule dynamics and cytoskeletal organization. CAPN6 has also been recently identified as an HIV dependency factor (HDF), suggesting that CAPN6 may be an important drug target in HIV treatment.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP2-06797
Species: Hu
NB100-553
Species: Hu, Mu
Applications: WB, IHC-P
NBP2-33443
Species: Hu
Applications: IHC, IHC-P
H00058508-R04
Species: Hu
H00000825-M01
Species: Hu
Applications: WB, ELISA, ICC/IF
NBP1-28875
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
AF3926
Species: Hu, Mu, Rt
Applications: WB
NBP1-83323
Species: Hu
Applications: WB, IHC, IHC-P
248-BD/CF
Species: Hu, Mu, Rt, Ca, Eq
AF674
Species: Hu
Applications: WB, Simple Western, Neut
NB100-236
Species: Hu, Mu
Applications: WB, IB, IHC, IHC-Fr, IHC-P, IP
NB100-2369
Species: Hu
Applications: ICC/IF, IHC
AF1180
Species: Hu
Applications: WB, Simple Western, IHC, ICC
NBP2-37576
Species: Hu, Mu, Pm
Applications: WB, ELISA, Flow, ICC/IF, IHC
NBP1-83220
Species: Hu, Mu, Rt
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
NBP2-13963
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-21577
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P, IP
NBP1-89200
Species: Hu, Mu
Applications: WB, Simple Western, IHC, IHC-P
NBP2-24529
Species: Hu, Mu, Ca, Ch, Pm
Applications: WB, Simple Western, IHC-P
NBP1-76937
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P

Publications for Calpain 6 Antibody (NBP1-76937) (0)

There are no publications for Calpain 6 Antibody (NBP1-76937).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for Calpain 6 Antibody (NBP1-76937) (0)

There are no reviews for Calpain 6 Antibody (NBP1-76937). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Calpain 6 Antibody (NBP1-76937) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional Calpain 6 Products

Bioinformatics Tool for Calpain 6 Antibody (NBP1-76937)

Discover related pathways, diseases and genes to Calpain 6 Antibody (NBP1-76937). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for Calpain 6 Antibody (NBP1-76937)

Discover more about diseases related to Calpain 6 Antibody (NBP1-76937).
 

Pathways for Calpain 6 Antibody (NBP1-76937)

View related products by pathway.

PTMs for Calpain 6 Antibody (NBP1-76937)

Learn more about PTMs related to Calpain 6 Antibody (NBP1-76937).

Blogs on Calpain 6

There are no specific blogs for Calpain 6, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Calpain 6 Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol CAPN6
Uniprot