Calcitonin Antibody Summary
Synthetic human calcitonin 1-32.
This stains specifically for human parafollicular cells (C-cells) of normal and hyperplastic thyroid as well as medullary thyroid carcinoma. No staining of other cells or tissues has been observed.
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- Western Blot
Immunohistochemistry -Paraffin 1:75-1:150. Immunoblotting 1:200-1:500. ELISA 1:300-1:3000.The optimal staining conditions should be determined by the individual laboratory. This antibody does not require heat mediated antigen retrieval before staining.
Cross-reacts with Human. Not yet tested in other species.
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
20mM Sodium Phosphate (pH 7.3) and 0.1M NaCl
0.05% Sodium Azide
Alternate Names for Calcitonin Antibody
- ATP2B2plasma membrane calcium ATPase
- ATPase, Ca++ transporting, plasma membrane 4
- EC 3.6.3
- EC 22.214.171.124
- Matrix-remodeling-associated protein 1
- matrix-remodelling associated 1
- Plasma membrane calcium ATPase isoform 4
- Plasma membrane calcium pump isoform 4
- plasma membrane calcium pump
- plasma membrane calcium-transporting ATPase 4
- sarcolemmal calcium pump
Calcitonin is a 32 amino acid peptide hormone synthesized by the parafollicular cells of the thyroid. It causes a rapid, but short lived, reduction in serum calcium and phosphate by promoting the incorporation of those ions in the bones. This effect is opposite to that of parathyroid hormone. Staining for calcitonin may be used for the identification of a spectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors. Staining for calcitonin in medullary carcinoma of the thyroid produces a fine granular pattern in the cytoplasm. Amyloid deposits within the tumor may also exhibit varying degrees of calcitonin activity.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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