The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
74 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Read 1 Review rated 4 using NBP2-17011 in the following application:
Human. Expected to cross react based on sequence identity: Chicken (85%), Bovine (98%), Mouse (97%), Rat (98%)
Alternate Names for Cadherin-6/KCAD Antibody
cadherin 6, type 2, K-cadherin (fetal kidney)
cadherin, fetal kidney
K-cadherin (fetal kidney)
This gene encodes a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of this gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion. [provided by RefSeq]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
5% non-fat milk in TBS buffer, room temperature for 1hour
1:1000 in 5% non-fat milk in TBS buffer overnight at 4C
Goat anti-rabbit IgG, HRP
Secondary Manufacturer Cat#
Cell Signaling, #7074
1 min exposure show strong band.
I am not 100% sure if the band show up is Cadherin-6 since the molecular weight is off. The band is very strong in T47D cells, but no signal in MCF7 cells. More experiments are needed to confirm the result.
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